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EMAGE:5061

Smad6 MAD homolog 6 (Drosophila) ( MGI:1336883)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5061
Figure 5M. Copyright: This image is from Ma L; Lu MF; Schwartz RJ; Martin JF, Development 2005; 132: 5601-11 [doi:10.1242/dev.02156] and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:16314491]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: ba1 - branchial arch 1; v - ventricle; a - atrium; arrow - positive hybridization signal or areas where signal is up- or downregulated in Bmp2 CKO mutant embryos.
Expression Pattern Description
Spatial Annotation:
EMAGE:5061Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5061_wholemount_moderate_3D_1.wlz
5061_wholemount_possible_3D_1.wlz
5061_wholemount_notDetected_3D_1.wlz
5061_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5061_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
atrioventricular canal
detected detected
Smad6 is expressed in the AV (atrio-venticular) endocardium
common atrial chamber endocardial lining
detected detected
regionalSmad6 is expressed in the AV (atrio-venticular) endocardium
primitive ventricle endocardial lining
detected detected
regionalSmad6 is expressed in the AV (atrio-venticular) endocardium
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Smad6 probeA
Entity Detected:Smad6, MAD homolog 6 (Drosophila) ( MGI:1336883)
Notes:The Smad6 probe used in this study by Ma et al., 2005 [PMID:16314491] is of unpublished sequence (details are available upon request).
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ma L; Lu MF; Schwartz RJ; Martin JF, 2005 [PMID:16314491] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.02156] [ PMID:16314491] Ma L, Lu MF, Schwartz RJ, Martin JF 2005 Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development (132):5601-11
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE