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EMAGE:5099

Sox8 SRY-box containing gene 8 ( MGI:98370)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5099
Fig4C. Schepers GE; Bullejos M; Hosking BM; Koopman P. 2000 "Cloning and characterisation of the Sry-related transcription factor gene Sox8". Nucleic Acids Res 28:1473-80. [PMID:10684944] .

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5099Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5099_wholemount_moderate.wlz
5099_wholemount_weak.wlz
5099_wholemount_possible.wlz
5099_wholemount_notDetected.wlz
5099_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5099_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
olfactory pit
strong strong
Strong expression was observed at 10.5 d.p.c. in the ventral nasal invaginations
branchial arch
strong strong
Strong expression was observed at 10.5 d.p.c. in the branchial arches
limb
strong strong
Strong expression was observed at 10.5 d.p.c. in the limbs
eye
strong strong
Strong expression was observed at 10.5 d.p.c. in the eye
dorsal root ganglion
strong strong
Strong expression was observed at 10.5 d.p.c. in the dorsal root ganglia
future spinal cord
strong strong
regionalStrong expression was observed at 10.5 d.p.c. in two parallel stripes at the lateral margins of the dorsal spinal cord
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Sox8 probeA
Entity Detected:Sox8, SRY-box containing gene 8 ( MGI:98370)
Sequence:sense strand is shown

>Sox8 probeA
TCAGCAAGACCCTAGGCAAGCTGTGGCGGTGAGTGTGGGGACTCTTGACACTCAGGCTGAGGAAAGGAGT
GACTTCGTGCCCCAGCTTGGGCTGTGCTCCTGGGCTGGTTCCAGGGTGGGTCTGGTCAACAGAGACACCA
GGTGTGGGACTTTGGAGATGGACGGAGGCCAGTGCCTGGAGTGTGACCCTCCAGTCCTTTCTCCTCTCCT
GGGATATCCTGCTGAGAACTGCAGAACTGGGGATCCTAGCATCGAGTGGCCACCACGGCCTGTAGGCATA
TTGGGTAGGCATCAAGCTGCTTTGTCCTGGGCAGAAGCTGGGACTCCGGGGTCCATGAGGAGTCCAAGTC
CTCTGGCAGGTACTGCTCCCAGGCCACAGGAACCTGGAATTGGGGAAGGAAAGAGCAGGTGAAAGTGACA
GGCTCAATGAGCACTTTGGCCTGAGAAAGGCAGGCATTATTGAAGACAGCTGCACAGTCCCACCTCCCAA
GCTGCCTCTATTCGAGTTTGAAACAGTGTGTAGTAGTGATACTGGGCTGAGCAGGACAGCCAGGTTGTCT
T
nt 1546 - nt 2106 of AF191325.1
Notes:The Sox8 probe used in this study by Schepers et al., 2000 [PMID:10684944] is described as "from the 3'-UTR and coding sequence (nucleotides 1546-2106)". Editors Note: the authors do not refer these co-ordinates to a defined sequence however elsewhere in the manuscript they do refer nucleotide co-ordinates of other fragments to AF191325.1, a genomic clone which includes several Sox8 exons.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Schepers GE; Bullejos M; Hosking BM; Koopman P. 2000 [PMID:10684944] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1093/nar/28.6.1473] [ PMID:10684944] Schepers GE, Bullejos M, Hosking BM, Koopman P 2000 Cloning and characterisation of the Sry-related transcription factor gene Sox8. Nucleic Acids Res (28):1473-80
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE