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EMAGE:5106

Spint1 serine protease inhibitor, Kunitz type 1 ( MGI:1338033)
TS17 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5106
Fig6E,HAE-1,right. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2006.11.005] Dev Biol 303: 222-30, Fan B; Brennan J; Grant D; Peale F; Rangell L; Kirchhofer D, "Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth." Copyright 2007 [PMID:17174946]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrows point to expression in limb bud (red), branchial arches (black) and otic vesicle (blue).
Expression Pattern Description
Spatial Annotation:
EMAGE:5106Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5106_wholemount_moderate.wlz
5106_wholemount_weak.wlz
5106_wholemount_possible.wlz
5106_wholemount_notDetected.wlz
5106_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5106_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
branchial arch
detected detected
ear
detected detected
Expressed in otic vesicle
limb
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Spint1 probeA
Entity Detected:Spint1, serine protease inhibitor, Kunitz type 1 ( MGI:1338033)
Sequence:sense strand is shown

>Spint1 probeA
AGCACCTGGTCTATAATCACACAACCCAGCCTCTCTGAGCCTGGGACTCTTGCCAGTCTTACCAGGTCCT
GCTTGCCAAGACAGAAGCTAGAACCTGGAAAAACTTGGGGACCAGACTCTTCCTACCTCTTTCCTGGGCA
TACTTACTCTGTCTCAGAAGACAGATCTCTGGGCCTCTCGCAGGAGTCTCAGCTGCACTCAGGCCAGTTC
TGGAGAAGGCCCAAGAGTCTGGAAGGAGCAGAGCAGCCTTGAGCCAGGAGTACTGTATATAGAAGGACCT
GCTTATCCAAGAGCTGGAGAAAGTTGGTGTTTTGTGTCTTGTTCAAAGCTGCCCATCACCATCCGATGAC
GCTAGGACCTTGAGTGGTATCAGAGGCCAGAAGCCACACACTGCCTTCCACATCTGTCCCTCCACTCTGC
AACAGGCTGAAGGATGTGTGTCTCTGCACACACTGAAGGATGTGTCTTTGTAGTTTGTGCTGTAAATAAT
T
Notes:The Spint1 (HAE-1) probe used in this study by Fan et al., 2007 [PMID:17174946] was "prepared from a murine HAI-1 partial cDNA clone (GenBank accession no. AA739106)."
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Fan B; Brennan J; Grant D; Peale F; Rangell L; Kirchhofer D. 2007 [PMID:17174946] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2006.11.005] [ PMID:17174946] Fan B, Brennan J, Grant D, Peale F, Rangell L, Kirchhofer D 2007 Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol (303):222-30
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE