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EMAGE:5131

Bach2 BTB and CNC homology 2 ( MGI:894679)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5131 EMAGE:5131 EMAGE:5131
Fig3B of Mol Cell Biol 2000 20(5): 1733-1746 [PMID:10669750] Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K, "A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain." © ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2000. Fig3F of Mol Cell Biol 2000 20(5): 1733-1746 [PMID:10669750] Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K, "A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain." © ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2000. Fig3I of Mol Cell Biol 2000 20(5): 1733-1746 [PMID:10669750] Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K, "A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain." © ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2000.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Fig3F and Fig3I are magnifications of the limbs as indicated by arrowheads in Fig3B.
Expression Pattern Description
Spatial Annotation:
EMAGE:5131Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5131_wholemount_moderate.wlz
5131_wholemount_weak.wlz
5131_wholemount_notDetected.wlz
5131_wholemount_strong.wlz
5131_wholemount_possible.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5131_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
forelimb bud apical ectodermal ridge
strong strong
Bach2 mRNAs were expressed strongly in the limb buds of 10.5-dpc mouse embryos. Bach2 mRNA showed a broad pattern of expression within the limb buds, however, the expression increased toward the edges of limb buds, where the AER is located.
hindlimb bud apical ectodermal ridge
strong strong
Bach2 mRNAs were expressed strongly in the limb buds of 10.5-dpc mouse embryos. Bach2 mRNA showed a broad pattern of expression within the limb buds, however, the expression increased toward the edges of limb buds, where the AER is located.
hindlimb bud
strong strong
Bach2 mRNAs were expressed strongly in the limb buds of 10.5-dpc mouse embryos. Bach2 mRNA showed a broad pattern of expression within the limb buds, however, the expression increased toward the edges of limb buds, where the AER is located.
forelimb bud
strong strong
Bach2 mRNAs were expressed strongly in the limb buds of 10.5-dpc mouse embryos. Bach2 mRNA showed a broad pattern of expression within the limb buds, however, the expression increased toward the edges of limb buds, where the AER is located.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Bach2 probeA
Entity Detected:Bach2, BTB and CNC homology 2 ( MGI:894679)
Notes:The Bach2 probe used in this study by Kobayashi et al., 2000 [PMID:10669750] is described as "nucleotides 232 to 793". Editors note: the authors do not refer these nucleotide co-ordinates to any particular sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K, 2000 [PMID:10669750] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1128/MCB.20.5.1733-1746.2000] [ PMID:10669750] Kobayashi A, Yamagiwa H, Hoshino H, Muto A, Sato K, Morita M, Hayashi N, Yamamoto M, Igarashi K 2000 A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain. Mol Cell Biol (20):1733-46
 [ doi:10.1016/0012-1606(90)90211-Z] [ PMID:2318343] H�bert JM, Basilico C, Goldfarb M, Haub O, Martin GR 1990 Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev Biol (138):454-63
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE