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EMAGE:5134

Ptprg protein tyrosine phosphatase, receptor type, G ( MGI:97814)
TS18 (10.5 dpc)
in situ reporter

Data Images
EMAGE:5134
Fig2B E10.5 of [doi:10.1128/MCB.00101-06] Mol Cell Biol 2006 26(13): 5106-5119 [PMID:16782895] Lamprianou S; Vacaresse N; Suzuki Y; Meziane H; Buxbaum JD; Schlessinger J; Harroch S, "Receptor Protein Tyrosine Phosphatase gamma Is a Marker for Pyramidal Cells and Sensory Neurons in the Nervous System and Is Not Necessary for Normal Development." © ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Arrow points to the isthmus. T - telencephalon (Editors Note: what the authors have labelled the telencephalon is actually the diencephalon).
Expression Pattern Description
Spatial Annotation:
EMAGE:5134Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5134_wholemount_moderate_3D_1.wlz
5134_wholemount_weak_3D_1.wlz
5134_wholemount_possible_3D_1.wlz
5134_wholemount_notDetected_3D_1.wlz
5134_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5134_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
neural tube
not detected not detected
homogeneous
midbrain
detected detected
regionalExpression is detected at the isthmus
hindbrain
detected detected
regionalExpression is detected at the isthmus
nose
detected detected
cardiovascular system
detected detected
regionalDistinct labeling of the vascular system of the brain was observed
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Ptprg, protein tyrosine phosphatase, receptor type, G ( MGI:97814)
Notes:Ptprg (RPTP-gamma) expression in this study by Lamprianou et al. 2006 [PMID:16782895] was assayed in embryos heterozygous for an mutant allele made using a targeting vector designed to insert an IRES-Betageo immediately downstream of exon 1.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129S6/SvEvTac * C57BL/6
Age:10.5 dpc
Theiler Stage:TS18
Mutations:Ptprgtm1Shar/Ptprg+
Preparation:wholemount
Procedures
Fixation:2% PFA, 0.2% glutaraldehyde
General Information
Authors:Lamprianou S; Vacaresse N; Suzuki Y; Meziane H; Buxbaum JD; Schlessinger J; Harroch S, 2006 [PMID:16782895] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1128/MCB.00101-06] [ PMID:16782895] Lamprianou S, Vacaresse N, Suzuki Y, Meziane H, Buxbaum JD, Schlessinger J, Harroch S 2006 Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development. Mol Cell Biol (26):5106-19
Links:MGI:3663183 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE