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EMAGE:5145

Dlg1 discs, large homolog 1 (Drosophila) ( MGI:107231)
TS17 (10.5 dpc)
in situ reporter

Data Images
EMAGE:5145
Fig2E of [doi:10.1128/MCB.21.5.1475-1483.2001] Mol Cell Biol 2001 21(5):1475-1483 [PMID:11238884] Caruana G; Bernstein A, "Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene." © ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM.Copyright 2001.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: b1 and b2, branchial arches 1 and 2, respectively; e, eye; h, heart; lb, limb bud; m, maxillary component of b1; np, nasal pit; tb, tailbud; t, telencephalon; op, otic pit; s, somites. Bar = 500 um
Expression Pattern Description
Spatial Annotation:
EMAGE:5145Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5145_wholemount_moderate_3D_1.wlz
5145_wholemount_weak_3D_1.wlz
5145_wholemount_notDetected_3D_1.wlz
5145_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5145_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
eye
detected detected
branchial arch
detected detected
limb
detected detected
hindlimb bud apical ectodermal ridge
detected detected
forelimb bud apical ectodermal ridge
detected detected
tail
detected detected
Expression was detected in the tailbud.
otocyst
detected detected
Expression was observed in the otic vesicle.
olfactory pit
detected detected
Expression was observed in the nasal pit.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Dlg1, discs, large homolog 1 (Drosophila) ( MGI:107231)
Notes:Dlg1 (dlg) expression was detected in this study by Caruana & Bernstein, 2001 [PMID:11238884] in embryos heterozygous for a gene-trap mutation where the gene trap vector was inserted into a position corresponding to 1653 of the encoded transcript. A fusion transcript that encodes part of the endogenous protein fused to beta-galactosidase is expressed from this allele.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129S1/Sv * 129X1/SvJ * ICR
Age:10.5 dpc
Theiler Stage:TS17
Mutations:Dlg1Gt(gt1.8geo)1Ber/Dlg1+
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Caruana G; Bernstein A, 2001 [PMID:11238884] , Indexed by GXD, Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1128/MCB.21.5.1475-1483.2001] [ PMID:11238884] Caruana G, Bernstein A 2001 Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene. Mol Cell Biol (21):1475-83
Links:MGI:2680670 allele description
 MGI:3698945 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI