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EMAGE:5173

Tlx1 T-cell leukemia, homeobox 1 ( MGI:98769)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5173
Fig3C. [doi:10.1093/hmg/ddh304] Kelly RG; Jerome-Majewska LA; Papaioannou VE "The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis" 2004 Hum Mol Genet 13(22):2829-40 [PMID:15385444]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5173Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5173_wholemount_moderate.wlz
5173_wholemount_possible.wlz
5173_wholemount_notDetected.wlz
5173_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5173_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch mandibular component mesenchyme
detected detected
Tlx1 is expressed in the mesodermal core
2nd branchial arch mesenchyme
detected detected
single cellTlx1 is expressed in the mesodermal core
1st branchial arch mandibular component ectoderm
detected detected
regional
Annotation Validation: Submitter + EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Tlx1 probeA
Entity Detected:Tlx1, T-cell leukemia, homeobox 1 ( MGI:98769)
Sequence:sense strand is shown

>Tlx1 probeA
GGATCCCCAGGCAGCCATCTGTACTAAAGCTGGAAACCTCTCTGTTCCTCTCCTCGGAGGAGAGCCCGGA
GGTCCACACAGAGGTGATACCACTGTCCCTCCTGGTGTCACCCAGAGCTACACACAGGGGCCTATGGCAG
AGCATCAATGCACACACAGGATCACAGCAAATGACCCTTGTTGTAGGGCATAGTCTGGGGTGACTCTCAG
ACTCACCCAAACAGCACGGACCTCAAACACACGGCCATAGTCACACTGTGACACACACAACAGCTAAACT
TGGCCTGTCAGGCCCTCAGCCACACATCCCAGCATCACCCAGGTCACCCAGGTCACCCAGGTATGCACAG
ACAGGCTTTCACATAAATGCAGCCCATTTCTCCAGATCCTGTTTGGGGAGGGGGGTAAGTTATGCCCTTA
TAAGTTATGCGCTTATAAGGTGTTTTCTGTGTAACCATTTTATAAAGTGCTTGTGTAATTTATGTGGAAA
AATAATAAAAGCCTCTGGATCAGGAAAAAAAAAAAAAAAATAAAAAAAAAAAAAAAAAAAAA
nt 1516 - nt 2067 of BC018246.1
Notes:The Tlx1 probe used in this study by Kelly et al., 2004. [PMID:15385444] was "was synthesized using T7 RNA polymerase and BamHI digested IMAGE clone 4164519". Editors note: BamHI cuts the insert sequence of IMAGE:4164519 (BC018246.1) internally, at position 1516.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:involves: 129/Sv * C57BL/6
Age:9.5 dpc
Theiler Stage:TS15
Mutations:Tbx1tm1Pa/Tbx1+
Preparation:wholemount
Procedures
General Information
Authors:Kelly RG; Jerome-Majewska LA; Papaioannou VE. 2004. [PMID:15385444] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1093/hmg/ddh304] [ PMID:15385444] Kelly RG, Jerome-Majewska LA, Papaioannou VE 2004 The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis. Hum Mol Genet (13):2829-40
Links:MGI:2179190 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE