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EMAGE:5174

Tlx1 T-cell leukemia, homeobox 1 ( MGI:98769)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:5174
Fig2a [doi:10.1038/368747a0] Roberts CW; Shutter JR; Korsmeyer SJ "Hox11 controls the genesis of the spleen." 1994 Nature 368(6473):747-9 [PMID:7908720] © Nature Publishing Group. Reproduced with permission from Nature.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: arrow - expression within the splanchnic mesoderm
Expression Pattern Description
Spatial Annotation:
EMAGE:5174Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5174_wholemount__moderate.wlz
5174_wholemount__possible.wlz
5174_wholemount__notDetected.wlz
5174_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5174_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
dorsal mesogastrium
detected detected
regionalExpression is present within a highly localized portion of the splanchnic mesoderm.
cranial ganglion
detected detected
regionalExpression is present within the branchial motor nuclei in the hindbrain
3rd branchial groove
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3760079
Entity Detected:Tlx1, T-cell leukemia, homeobox 1 ( MGI:98769)
Notes:The Tlx1 (Hox11) probe used in this study by Roberts et al., 1994 [PMID:7908720] is described as "a 450-bp probe beginning 3' of the homeobox and continuing into the 3' untranslated region defined by the upstream sequence 5'-AGAGGAACGTGAGGCCGAGA-3' and downstream sequence 5'-GGATCCCAGAAGCCTTCCGG-3'.". Editors note: Pair-wise BLAST of these sequences against the mouse Tlx1 cDNA RefSeq NM_021901.2 suggests a 520bp region extends between these two sequences (nt 993-1521 of NM_021901.2).
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Roberts CW; Shutter JR; Korsmeyer SJ. 1994 [PMID:7908720] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/368747a0] [ PMID:7908720] Roberts CW, Shutter JR, Korsmeyer SJ 1994 Hox11 controls the genesis of the spleen. Nature (368):747-9
Links:MGI:3760080 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI