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EMAGE:5175

Tlx2 T-cell leukemia, homeobox 2 ( MGI:1350935)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5175
Fig4c Tang SJ; Suen TC; McInnes RR; Buchwald M 1998 "Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins." J Biol Chem 273(39):25356-63 [PMID:9738002] .

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5175Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5175_wholemount_moderate.wlz
5175_wholemount_weak.wlz
5175_wholemount_possible.wlz
5175_wholemount_notDetected.wlz
5175_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5175_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
cranial ganglion
detected detected
dorsal root ganglion
detected detected
sympathetic nervous system
detected detected
expressed in the sympathetic ganglia
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Tlx2 probeA
Entity Detected:Tlx2, T-cell leukemia, homeobox 2 ( MGI:1350935)
Notes:The Tlx2 probe used in this study by Tang et al., 1998 [PMID:9738002] is described as follows: "For generating the Tlx-2 antisense riboprobe, pGEM7-Tlx-2/SacIIA was linearized with NotI and transcribed with T7 polymerase". Editors Note: Elsewhere the authors state that "For pBSKS(-)-Tlx-2/SacIIA, the 284-base pair SacII fragment from the Tlx-2 genomic clone was cloned into the SacII site of pBSKS(-), oriented with the 5'-end next to the T3 promoter". It is not specified whether the insert of the GEM and Blusecript SacIIA clones is the same fragment.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Tang SJ; Suen TC; McInnes RR; Buchwald M. 1998 [PMID:9738002] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1074/jbc.273.39.25356] [ PMID:9738002] Tang SJ, Suen TC, McInnes RR, Buchwald M 1998 Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins. J Biol Chem (273):25356-63
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE