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EMAGE:5176

Tlx3 T-cell leukemia, homeobox 3 ( MGI:1351209)
TS18 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5176
Fig1a [doi:10.1038/73516] Shirasawa S; Arata A; Onimaru H; Roth KA; Brown GA; Horning S; Arata S; Okumura K; Sasazuki T; Korsmeyer SJ 2000 "Rnx deficiency results in congenital central hypoventilation." Nat Genet 24(3):287-90 [PMID:10700185] © Nature Publishing Group. Reproduced with permission from Nat Genet.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Rnx RNA detected in Vth (arrowhead), VIIth-VIIIth (short arrow), IXth (middle arrow) and Xth (long arrow) ganglia.
Expression Pattern Description
Spatial Annotation:
EMAGE:5176Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5176_wholemount__moderate.wlz
5176_wholemount__weak.wlz
5176_wholemount__possible.wlz
5176_wholemount__notDetected.wlz
5176_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5176_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
trigeminal v ganglion
detected detected
facial vii ganglion
detected detected
acoustic viii ganglion
detected detected
glossopharyngeal ix ganglion
detected detected
vagus x ganglion
detected detected
dorsal root ganglion
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Tlx3 probeA
Entity Detected:Tlx3, T-cell leukemia, homeobox 3 ( MGI:1351209)
Notes:The Tlx3 (Rnx) probe used in this study by Shirasawa et al., 2000 [PMID:10700185] was "a digoxigenin-labelled 548-nt anti-sense probe of Rnx 3' UTR sequence"
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS18
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Shirasawa S; Arata A; Onimaru H; Roth KA; Brown GA; Horning S; Arata S; Okumura K; Sasazuki T; Korsmeyer SJ . 2000 [PMID:10700185] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/73516] [ PMID:10700185] Shirasawa S, Arata A, Onimaru H, Roth KA, Brown GA, Horning S, Arata S, Okumura K, Sasazuki T, Korsmeyer SJ 2000 Rnx deficiency results in congenital central hypoventilation. Nat Genet (24):287-90
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE