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EMAGE:5179

Tmod1 tropomodulin 1 ( MGI:98775)
TS15 (9.5 dpc)
in situ reporter

Data Images
EMAGE:5179
Fig2A_9.5 of [doi:10.1083/jcb.200308164] Copyright: This image is from Fritz-Six KL; Cox PR; Fischer RS; Xu B; Gregorio CC; Zoghbi HY; Fowler VM "Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality." J Cell Biol 2003 163(5): 1033-44 [PMID:14657235] , and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5179Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5179_wholemount_moderate.wlz
5179_wholemount_weak.wlz
5179_wholemount_notDetected.wlz
5179_wholemount_strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5179_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
heart
detected detected
Expression is only detected in the heart
branchial arch
not detected not detected
homogeneous
body cavity or lining
not detected not detected
homogeneous
embryo ectoderm
not detected not detected
homogeneous
limb
not detected not detected
homogeneous
mesenchyme
not detected not detected
homogeneous
notochord
not detected not detected
homogeneous
nervous system
not detected not detected
homogeneous
sensory organ system
not detected not detected
homogeneous
arterial system
not detected not detected
homogeneous
venous system
not detected not detected
homogeneous
visceral organ system
not detected not detected
homogeneous
skeleton
not detected not detected
homogeneous
tail
not detected not detected
homogeneous
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Tmod1, tropomodulin 1 ( MGI:98775)
Notes:Tmod1 expression was assayed in this study by Fritz-Six et al., 2003 [PMID:14657235] in embryos heterozygous for a targeted mutation where exon 2 was replaced with a cassette containing both lacZ and neo. Protein was undetected by Western blot analysis of homozygous mutant embryos.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129S7/SvEvBrd * C57BL/6J
Age:9.5 dpc
Theiler Stage:TS15
Mutations:Tmod1tm1Vmf/Tmod1+
Preparation:wholemount
Procedures
General Information
Authors:Fritz-Six KL; Cox PR; Fischer RS; Xu B; Gregorio CC; Zoghbi HY; Fowler VM. 2003 [PMID:14657235] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1083/jcb.200308164] [ PMID:14657235] Fritz-Six KL, Cox PR, Fischer RS, Xu B, Gregorio CC, Zoghbi HY, Fowler VM 2003 Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. J Cell Biol (163):1033-44
Links:MGI:2687078 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE