EMAGE mouse gene expression spatial database

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EMAGE:5185

Trp63 transformation related protein 63 ( MGI:1330810)
TS18 (10.5 dpc)
in situ hybridisation

Data Images


Fig 2b [doi:10.1038/19539] Mills AA; Zheng B; Wang XJ; Vogel H; Roop DR; Bradley A "p63 is a p53 homologue required for limb and epidermal morphogenesis." 1999 Nature 398(6729):708-13 [PMID:10227293] © Nature Publishing Group. Reproduced with permission from Nature.	Fig 2b [doi:10.1038/19539] Mills AA; Zheng B; Wang XJ; Vogel H; Roop DR; Bradley A "p63 is a p53 homologue required for limb and epidermal morphogenesis." 1999 Nature 398(6729):708-13 [PMID:10227293] © Nature Publishing Group. Reproduced with permission from Nature.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

b, Whole-mount in situ hybridisation of a wild-type, E10.5 embryo with a p63 RNA probe, showing strong transcript expression in the branchial arches (upper right) and developing limb bud (lower right).

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

5185_wholemount__moderate.wlz

5185_wholemount__weak.wlz

5185_wholemount__possible.wlz

5185_wholemount__notDetected.wlz

5185_wholemount__strong.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:5185_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

branchial arch

strong

limb

strong

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	Trp63 probeB
Entity Detected:	Trp63, transformation related protein 63 ( MGI:1330810)
Sequence:	sense strand is shown >Trp63 probeB ATGTTGTACCTGGAAAACAATGCCCAGACTCAATTTAGTGAGCCACAGTACACGAACCTGGGGCTCCTGA ACAGCATGGACCAGCAGATTCAGAACGGCTCCTCGTCCACCAGCCCCTACAACACAGACCACGCACAGAA TAGCGTGACGGCGCCCTCGCCCTATGCACAGCCCAGCTCCACCTTTGATGCCCTCTCTCCATCCCCTGCC ATTCCCTCCAACACAGATTACCCGGGCCCACACAGCTTCGATGTGTCCTTCCAGCAGTCAAGCACTGCCA AGTCAGCCACCTGGACGTATTCCACCGAACTGAAGAAGCTGTACTGCCAGATTGCGAAGACATGCCCCAT CCAGATCAAGGTGATGACCCCACCCCCACAGGGCGCTGTTATCCGTGCCATGCCTGTCTACAAGAAAGCT GAGCATGTCACCGAGGTTGTGAAACGATGCCCTAACCATGAGCTGAGCCGTGAGTTCAATGAGGGACAGA TTGCCCCTCCCAGTCATCTGATTCGAGTAGAAGGGAACAGCCATGCCCAGTATGTAGAAGATCCTATCAC GGGAAGGCAGAGCGTGCTGGTCCCTTATGAGCCACCACAGGTTGGCACTGAATTCACAACAGTCCTGTAC AATTTCATGTGTAACAGCAGCTGCGTCGGAGGAATGAACAGACGTCCAATTTTAATCATCGTTACTCTGG AAACCAGAGATGGGCAAGTCCTGGGCCGACGGTGCTTTGAGGCCCGGATCTGTGCTTGCCCAGGAAGAGA CCGGAAGGCAGATGAAGACAGCATCAGAAAGCAGCAAGTATCGGACAGCGCAAAGAACGGCGATGCTTTC CGTCAGAATACACACGGAATCCAGATGACTTCCATCAAGAAACGGAGATCCCCAGATGATGAGCTGCTGT ACCTACCAGTGAGAGGTCGTGAGACGTACGAGATGTTGCTGAAGATCAAAGAGTCACTGGAGCTCATGCA GTACCTCCCTCAGCACACGATCGAAACGTACAGGCAGCAGCAGCAGCAGCAGCACCAGCACCTACTTCAG AAACATCTCCTTTCAGCCTGCTTCAGGAATGAGCTTGTGGAGCCCCGGGGAGAAGCTCCGACACAGTCTG ACGTCTTCTTTAGACATTCCAACCCCCCAAACCACTCCGTGTACCCATAG
	nt 1 - nt 1170 of AF075437.1
Notes:	The Trp63 (p63) probe used in this study by Mills et al., 1999 [PMID:10227293] is indicated as "deltaNp63gamma (Yang et al., 1998 [PMID:9774969] )". Editors note: Yang et al state that the sequence of mouse deltaNp63gamma was deposited as AF075437.
Chemistry:	RNA
Strand:	antisense

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS18
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Mills AA; Zheng B; Wang XJ; Vogel H; Roop DR; Bradley A. 1999 [PMID:10227293] . Indexed and spatially mapped by EMAGE
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1038/19531] [ PMID:10227293] Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A 1999 p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (398):708-13
	[ doi:10.1016/S1097-2765(00)80275-0] [ PMID:9774969] Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F 1998 p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell (2):305-16
Links:	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source