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EMAGE:5190

Ttn titin ( MGI:98864)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5190
Fig1Ec of [doi:10.1083/jcb.200601014] Copyright: This image is from Weinert S; Bergmann N; Luo X; Erdmann B; Gotthardt M "M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere." J Cell Biol 2006 173(4): 559-70 [PMID:16702235] , and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5190Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5190_wholemount__moderate.wlz
5190_wholemount__weak.wlz
5190_wholemount__notDetected.wlz
5190_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5190_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
heart
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Titin probeB
Entity Detected:Ttn, titin ( MGI:98864)
Notes:The Ttn probe used in this study by Weinert et al., 2006 [PMID:16702235] was "a probe that recognizes a region upstream of the kinase domain (prekin)" - see Fig 1A therein for a schematic representation of the probe region.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Authors:Weinert S; Bergmann N; Luo X; Erdmann B; Gotthardt M. 2006 [PMID:16702235] . Indexed and spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1083/jcb.200601014] [ PMID:16702235] Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M 2006 M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol (173):559-70
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE