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EMAGE:5241

Egfr epidermal growth factor receptor ( MGI:95294)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5241
Fig3A. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.modgep.2004.08.004] Gene Expr Patterns 5(1): 3-9, Golding JP; Tsoni S; Dixon M; Yee KT; Partridge TA; Beauchamp JR; Gassmann M; Zammit PS, Heparin-binding EGF-like growth factor shows transient left-right asymmetrical expression in mouse myotome pairs. Copyright 2004. [PMID:15533812]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: apical ectodermal ridge of the limb bud (arrowhead) and heart (ht).
Expression Pattern Description
Spatial Annotation:
EMAGE:5241Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5241_wholemount_moderate_3D_1.wlz
5241_wholemount_weak_3D_1.wlz
5241_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5241_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
forelimb bud ectoderm
strong strong
regionalhigh expression in the apical ectodermal ridge of the limb bud.
heart
weak weak
embryo
detected detected
homogeneousErbB1 at E9.5 demonstrated uniform expression, except for relatively high expression in the apical ectodermal ridge of the limb bud (arrowhead in A) and relatively weak expression in the heart (ht). No obvious left-right differences in ErbB1 expression could be detected.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Egfr probeA
Entity Detected:Egfr, epidermal growth factor receptor ( MGI:95294)
Notes:The Egfr (ErbB1) probe used in this study by Golding et al., 2004 [PMID:15533812] is described as "rat ErbB1", "a gift of Cary Lai (Scripps Institute)", and is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Golding JP; Tsoni S; Dixon M; Yee KT; Partridge TA; Beauchamp JR; Gassmann M; Zammit PS, 2004 [PMID:15533812] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2004.08.004] [ PMID:15533812] Golding JP, Tsoni S, Dixon M, Yee KT, Partridge TA, Beauchamp JR, Gassmann M, Zammit PS 2004 Heparin-binding EGF-like growth factor shows transient left-right asymmetrical expression in mouse myotome pairs. Gene Expr Patterns (5):3-9
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE