EMAGE mouse gene expression spatial database

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EMAGE:5252

Enc1 ectodermal-neural cortex 1 ( MGI:109610)
TS14 (9.5 dpc)
in situ hybridisation

Data Images


Fig5F. Copyright: Reprinted with permission from the Society for Neuroscience from J Neurosci 17(9): 3038-51. Hernandez MC; Andres-Barquin PJ; Martinez S; Bulfone A; Rubenstein JL ; Israel MA. ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. Copyright 1997. [PMID:9096139]

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotations: The open arrow in f shows the restricted mesodermal ENC-1 expression to the rostral-most somitomere of the presomitic mesoderm. midbrain (MB); diencephalon (D); telencephalic vesicle (T).

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

5252_wholemount__moderate.wlz

5252_wholemount__weak.wlz

5252_wholemount__notDetected.wlz

5252_wholemount__strong.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:5252_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

prosencephalon

detected

regional

ENC-1 RNA expression was detected in the neuroepithelium of the caudal pole of the telencephalic vesicle.

rhombomere 01

detected

RNA expression was detected in the rostral rhombencephalon (pro-rhombomere A). Editors Note: Pro-rhombomere A develops into rhombomeres 1 and 1 around this time.

rhombomere 02

detected

RNA expression was detected in the rostral rhombencephalon (pro-rhombomere A). Editors Note: Pro-rhombomere A develops into rhombomeres 1 and 1 around this time.

unsegmented mesenchyme

detected

regional

There is restricted mesodermal ENC-1 expression to the rostral-most somitomere of the presomitic mesoderm (indicated by the open arrow).

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	Enc1 probeA
Entity Detected:	Enc1, ectodermal-neural cortex 1 ( MGI:109610)
Sequence:	sense strand is shown >Enc1 probeA CGCACGGTCACTCTCCCCTGGCTAGGCGCGCGCCGGCAGACGCTTGGCCCGGCCGGGGCGCCAGGTCCGT AGCAGCAGATCCGGAGACCGAGGTCAGCTGCCTGCCGAAACCAGCCCGGGAGCCACTACCCCGGACGCTA TCGCCTCCCTTCCCAGCGCTCCTTTCTCCCCGGCGATCGCCACCGCTTCCTGGAACAGAGACGCCCTTCG TCGGCTCCCTGCGGTGACCGAGGCAAGAACCGCAGCCGGTTGTGTGCAGAGGCCAGCCGCCACTACTGAG TTGAAACAAAATGTCAGTCAGTGTGCATGAGAACCGCAAGTCCAGGGCCAGCAGTGGCTCCATCAACATC TACCTGTTTCATAAGTCCTCCTACGCGGACAGCGTTCTCACTCACCTGAACCTTCTGCGTCAGCAGCGGC TCTTCACAGATGTCCTTCTCCATGCGGGAAACAGGACCTTCCCTTGCCACCGGGCAGTGCTGGCTGCGTG CAGCCGCTACTTCGAAGCCATGTTCAGTGGTGGCCTGAAAGAGAGCCAGGACAGTGAGGTGAACTTCGAC AATTCCATCCACCCAGAAGTCTTAGAGCTGCTTCTAGACTACGCATACTCCTCCCGGGTCATTATCAATG AAGAAAATGCTGAGTCGCTCCTGGAGGCTGGTGACATGCTGGAGTTCCAGGACATCAGAGATGCGTGTGC AGAATTTCTAGAGAAGAACCTGCATCCCACCAACTGCCTGGGTATGCTGCTGTTGTCTGATGCCCACCAG TGCACCAAGCTGTACGAACTCTCCTGGAGAATGTGTCTCAGCAACTTCCAAACCATTCGGAAGAGCGAAG ATTTCCTCCAGTTGCCCCAGGACATGGTTGTGCAGCTGCTGTCCAGTGAAGAACTGGAGACGGAAGACGA AAGGCTGGTGTATGAGTCTGCGATGAACTGGATCAGCTATGACCTGAAGAAGCGCTACTGTTACCTCCCG GAACTGTTGCAGACAGTGAGGCTGGCCCTCCTTCCTGCCATCTATCTCATGGAGAACGTGGCGATGGAAG AACTCATCACCAAGCAGAGAAAGAGTAAGGAGATCGTGGAAGAGGCCATCAGGTGCAAACTAAAAATCTT ACAGAATGACGGCGTGGTCACCAGTCTCTGTGCTCGTCCTCGGAAAACTGGCCATGCCCTGTTCCTCCTG GGAGGGCAGACTTTCATGTGTGACAAACTGTACTTGGTAGACCAGAAGGCTAAAGAAATCATTCCCAAGG CTGACATTCCCAGCCCGAGGAAAGAGTTCAGCGCATGTGCAATTGGCTGCAAAGTATATATTACTGGGGG GCGGGGATCAGAGAACGGAGTCTCAAAAGATGTCTGGGTTTACGATACCCTGCATGAGGAGTGGTCCAAG GCTGCCCCCATGCTGGTGGCCAGGTTTGGCCATGGATCTGCTGAACTGAAGCACTGCCTCTATGTAGTCG GTGGGCACACAGCTGCAACTGGCTGCCTCCCAGCCTCCCCCTCGGTCTCCCTAAAGCAAGTAGAACAGTA TGACCCCACAACCAACAAATGGACCATGGTAGCCCCACTCCGCGAAGGTGTCAGCAATGCTGCTGTAGTG AGTGCCAAACTTAAGCTGTTTGCTTTCGGGGGTACCAGTGTGAGCCACGACAAGCTGCCCAAGGTTCAGT GTTACGATCAATGCGAGAACAGATGGTCAGTGCCGGCCACCTGTCCCCAGCCCTGGCGTTACACAGCCGC AGCTGTGCTGGGAAACCAGATTTTTATCATGGGTGGAGATACAGAGTTCTCTGCCTGCTCCGCTTACAAA TTCAATAGTGAGACTTACCAGTGGACCAAGGTGGGAGATGTGACAGCCAAGCGCATGAGCTGCCACGCCG TGGCCTCCGGGAACAAGCTTTACGTAGTTGGAGGGTACTTCGGCATTCAGCGCTGCAAGACTTTGGACTG TTACGACCCAACTTTAGATGTGTGGAACAGCATAACCACTGTTCCCTACTCTCTGATCCCTACTGCATTC GTCAGCACCTGGAAACACCTGCCTTCCTAATGTAGAGCATCCTAAAGAAAGCACGCATGAGCTCATTCTG ATGCACGGCGAGATGAGATGTCATTTCTGCTTTGGAGAAGGCAAGTTTAATGAAGAGAAAGAAAAACAGG AGCAGTTGCTACTGAGACTCCTCGAATACCATCGGCTGCACCTTGCAAACACTCTCAAGTGGACATGAAG GAAGGGGTGGGGGGAGGGGCGGGTTTTTTTTTTTTTCAATATAAGTAGCACATGGTTTAA
	nt 1 - nt 2300 of U65079.1
Notes:	The Enc1 probe used in this study by Hernandez et al., 1997 [PMID:9096139] is described as follows: "the antisense ENC-1 riboprobe was synthesized using a digoxigenin RNA labeling kit (Boehringer Mannheim) and DNA from the clone p10.2x." Editors Note: see Fig2 therein and U65079.1 for the insert sequence of clone p10.2x. Note that U65079.1 does not include the long poly(A) tail shown in Fig2.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	9.5 dpc
Theiler Stage:	TS14
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

Staining procedure:

alkaline phosphatase + unspecified

General Information

Authors:	Hernandez MC; Andres-Barquin PJ; Martinez S; Bulfone A; Rubenstein JL ; Israel MA, 1997 [PMID:9096139] , Indexed and Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:9096139] Hernandez MC, Andres-Barquin PJ, Martinez S, Bulfone A, Rubenstein JL, Israel MA 1997 ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J Neurosci (17):3038-51
Links:	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source