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EMAGE:5275

Epo erythropoietin ( MGI:95407)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5275
Fig6I(inset) of [doi:10.1128/MCB.23.17.6103-6116.2003] Mol Cell Biol 2003 23(17):6103-16 [PMID:12917333] Otto DM; Henderson CJ; Carrie D; Davey M; Gundersen TE; Blomhoff R; Adams RH; Tickle C; Wolf CR, Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2003.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
The embryo shown is heterozygous for mutated CPR/Por (P450 (cytochrome) oxidoreductase) and was included in this study as a control.
Expression Pattern Description
Spatial Annotation:
EMAGE:5275Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5275_wholemount__moderate.wlz
5275_wholemount__weak.wlz
5275_wholemount__notDetected.wlz
5275_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5275_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
branchial arch
strong strong
heart
strong strong
dorsal aorta
detected detected
trunk somite
strong strong
tail
strong strong
future forebrain
strong strong
future midbrain
strong strong
future hindbrain
strong strong
cardiovascular system
strong strong
regionalEpo is highly expressed in the major blood vessels.
limb
strong strong
future brain
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Epo probeA
Entity Detected:Epo, erythropoietin ( MGI:95407)
Notes:The Epo probe used in this study by Otto et al., 2003 [PMID:12917333] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Age:9.5 dpc
Theiler Stage:TS15
Mutations:Portm2Wolf/Por+
Preparation:wholemount
Procedures
General Information
Authors:Otto DM; Henderson CJ; Carrie D; Davey M; Gundersen TE; Blomhoff R; Adams RH; Tickle C; Wolf CR, 2003 [PMID:12917333] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1128/MCB.23.17.6103-6116.2003] [ PMID:12917333] Otto DM, Henderson CJ, Carrie D, Davey M, Gundersen TE, Blomhoff R, Adams RH, Tickle C, Wolf CR 2003 Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. Mol Cell Biol (23):6103-16
Links:MGI:2656920 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE