Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:5299

Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) ( MGI:95411)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5299 EMAGE:5299
Fig4d [doi:10.1038/ng768] Nat Genet 2001 29(4): 469-74, Bamforth SD; Braganca J; Eloranta JJ; Murdoch JN; Marques FI; Kranc KR; Farza H; Henderson DJ; Hurst HC; Bhattacharya S, Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. 2001 [PMID:11694877] © Nature Publishing Group. Reproduced with permission from Nat Genet. Fig4g [doi:10.1038/ng768] Nat Genet 2001 29(4): 469-74, Bamforth SD; Braganca J; Eloranta JJ; Murdoch JN; Marques FI; Kranc KR; Farza H; Henderson DJ; Hurst HC; Bhattacharya S, Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. 2001 [PMID:11694877] © Nature Publishing Group. Reproduced with permission from Nat Genet.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Though the embryo shown is a heterozygote Cited2 mutant, the authors state that the staining pattern observed, represents a wild-type Erbb3 expression pattern. Image annotations: cranial ganglia (V, VII/VIII, IX, Xj (jugular), Xn (nodose)); dorsal root ganglia (drg); cardiac neural crest cells (CNCC); otic vesicle (ov).
Expression Pattern Description
Spatial Annotation:
EMAGE:5299Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5299_wholemount__moderate.wlz
5299_wholemount__weak.wlz
5299_wholemount__notDetected.wlz
5299_wholemount__strong.wlz
5299_wholemount__possible.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5299_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
dorsal root ganglion
detected detected
regionalErbB3 expression is detected in the neural crest cells of the developing dorsal root ganglia.
ear
detected detected
regionalErbB3 expression is detected in the otic vesicle.
3rd branchial arch mesenchyme derived from neural crest
detected detected
ErbB3 expressing CNCC are seen migrating through the third, fourth and sixth aortic arches (CNCC3, CNCC4 and CNCC6, respectively) towards the outflow tract of the heart.
4th branchial arch mesenchyme derived from neural crest
detected detected
ErbB3 expressing CNCC are seen migrating through the third, fourth and sixth aortic arches (CNCC3, CNCC4 and CNCC6, respectively in Fig4g) towards the outflow tract of the heart.
branchial arch
detected detected
regionalErbB3 expressing CNCC are seen migrating through the third, fourth and sixth aortic arches (CNCC3, CNCC4 and CNCC6, respectively) towards the outflow tract of the heart.
head mesenchyme derived from neural crest
detected detected
regionalErbB3 expression is detected in the migrating cardiac neural crest cells (CNCC), migrating through the third, fourth and sixth aortic arches (CNCC3, CNCC4 and CNCC6, respectively) towards the outflow tract of the heart.
facio-acoustic vii-viii ganglion complex
detected detected
regionalErbB3 expression is detected in the neural crest cells of the developing VII/VIII cranial ganglia.
glossopharyngeal ix ganglion
detected detected
regionalErbB3 expression is detected in the neural crest cells of the developing IX cranial ganglia.
vagus x ganglion
detected detected
ErbB3 expression is detected in the neural crest cells of the developing Xj (jugular/superior) and Xn (nodose/inferior) cranial ganglia.
trigeminal v ganglion
detected detected
ErbB3 expression is detected in the neural crest cells of the developing V cranial ganglia.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Erbb3 probeA
Entity Detected:Erbb3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) ( MGI:95411)
Notes:The Erbb3 probe used in this study by Bamforth et al., 2001 [PMID:11694877] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd
Age:10.5 dpc
Theiler Stage:TS16
Mutations:Cited2tm1Bha/Cited2+
Preparation:wholemount
Procedures
General Information
Authors:Bamforth SD; Braganca J; Eloranta JJ; Murdoch JN; Marques FI; Kranc KR; Farza H; Henderson DJ; Hurst HC; Bhattacharya S, 2001 [PMID:11694877] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/ng768] [ PMID:11694877] Bamforth SD, Braganca J, Eloranta JJ, Murdoch JN, Marques FI, Kranc KR, Farza H, Henderson DJ, Hurst HC, Bhattacharya S 2001 Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet (2001):469-74
Links:MGI:2179740 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE