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EMAGE:5324

Fadd Fas (TNFRSF6)-associated via death domain ( MGI:109324)
TS15 (10 dpc)
in situ hybridisation

Data Images
EMAGE:5324
Fig2A. from [doi:10.1126/science.279.5358.1954] Science 1998 279(5358): 1954-1958, Yeh WC; Pompa JL; McCurrach ME; Shu HB; Elia AJ; Shahinian A ; Ng M ; Wakeham A ; Khoo W ; Mitchell K ; El-Deiry WS ; Lowe SW ; Goeddel DV ; Mak TW, FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Copyright 1998 [PMID:9506948]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5324Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5324_wholemount__moderate.wlz
5324_wholemount__weak.wlz
5324_wholemount__possible.wlz
5324_wholemount__notDetected.wlz
5324_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5324_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
FADD expression is detected "in all tissues, particularly in the brain, developing somites, and facial mesenchyme".
future brain
strong strong
trunk somite
strong strong
regional
head mesenchyme
strong strong
regionalExpression is detected in the facial mesenchyme.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Fadd probeA
Entity Detected:Fadd, Fas (TNFRSF6)-associated via death domain ( MGI:109324)
Notes:The Fadd probe used in this study by Yeh et al., 1998 [PMID:9506948] is one of two described in the paper (it is not specified which was used for this exact experiment). i.e. either: "a 1.3-kb full-length murine FADD cDNA" or "a 0.8-kb 3' untranslated region fragment."
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Yeh WC; Pompa JL; McCurrach ME; Shu HB; Elia AJ; Shahinian A ; Ng M ; Wakeham A ; Khoo W ; Mitchell K ; El-Deiry WS ; Lowe SW ; Goeddel DV ; Mak TW, 1998 [PMID:9506948] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1126/science.279.5358.1954] [ PMID:9506948] Yeh WC, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wakeham A, Khoo W, Mitchell K, El-Deiry WS, Lowe SW, Goeddel DV, Mak TW 1998 FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science (279):1954-8
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE