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EMAGE:5351

Foxs1 forkhead box S1 ( MGI:95546)
TS17 (10.5 dpc)
in situ reporter

Data Images
EMAGE:5351 EMAGE:5351
Fig2C of [doi:10.1128/MCB.25.13.5616-5625.2005] Mol Cell Biol 2005 25(13):5616-25 [PMID:15964817] Heglind M; Cederberg A; Aquino J; Lucas G; Ernfors P; Enerback S, "Lack of the central nervous system- and neural crest-expressed forkhead gene foxs1 affects motor function and body weight." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2005. Fig2F of [doi:10.1128/MCB.25.13.5616-5625.2005] Mol Cell Biol 2005 25(13):5616-25 [PMID:15964817] Heglind M; Cederberg A; Aquino J; Lucas G; Ernfors P; Enerback S, "Lack of the central nervous system- and neural crest-expressed forkhead gene foxs1 affects motor function and body weight." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2005.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: Trigeminal (V), facio-acoustic (VII-VIII), petrosal (IXp) and nodose (Xn) ganglia. Glossopharyngeal (IX) and vagal (X) nerves. Arrows indicate signal in nasal region of C. Fig2f is of a section taken at the level indicated by the red line in Fig2c.
Expression Pattern Description
Spatial Annotation:
EMAGE:5351Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5351_wholemount__moderate.wlz
5351_wholemount__possible.wlz
5351_wholemount__notDetected.wlz
5351_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5351_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
nose
detected detected
regionalexpression is seen in the nasal region.
glossopharyngeal ix ganglion
detected detected
regionalExpression is detected in the petrosal ganglia of the glossopharyngeal nerve.
vagus x ganglion
detected detected
Expression is detected in the nodose ganglia of the vagal nerve.
dorsal root ganglion
detected detected
Compared to at E9.5, expression has extended to DRG along the rostro-caudal axis.
trigeminal v ganglion
detected detected
facial vii ganglion
detected detected
acoustic viii ganglion
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Foxs1, forkhead box S1 ( MGI:95546)
Notes:Foxs1 expression was detected in this study by Heglind et al., 2005 [PMID:15964817] in embryos heterozygous for a targeted allele in which an NLS-lacZ cassette was inserted after the first 16 amino acids of the locus, replacing the DNA binding region. Staining indicated that expression of lacZ reflected expression of endogenous protein.
Labelled with:LacZ
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:Foxs1tm1Sven/Foxs1+
Preparation:wholemount
Procedures
General Information
Authors:Heglind M; Cederberg A; Aquino J; Lucas G; Ernfors P; Enerback S, 2005 [PMID:15964817] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.modgep.2005.04.009] [ PMID:15979417] Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabe de Angelis M, Beckers J 2005 Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns (6):94-101
Links:MGI:3606198 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE