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EMAGE:5361

Zfp131 zinc finger protein 131 ( MGI:1919715)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5361 EMAGE:5361 EMAGE:5361 EMAGE:5361 EMAGE:5361
Figure 3D. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3A. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3E. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3F. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3G. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] .
EMAGE:5361 EMAGE:5361 EMAGE:5361 EMAGE:5361 EMAGE:5361
Figure 3G1. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3G2. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3H. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3H1. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] . Figure 3H2. [doi:10.1016/S0006-291X(02)00850-1] Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, "The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus." Biochem Biophys Res Commun 2002;296: 319-27. [PMID:12163020] .

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
(A) Znf131 sense probe shows no signal at 10.5dpc. (D) At 10.5 dpc, Znf131 signals are visible in the forebrain region (fb), the rostral apical midbrain (mb), the neural tube (nt), the fore limb (fl), and hind limb (hl). (E) A 10.5 dpc embryo shown from the upper back. Staining is detected especially in the neural fold (nf) of the perspective hindbrain (phb), the midbrain, and neural tube. (F) Identical to (D) but showing the planes of embryonic sections shown in figures 3G to 3H. (G) Transverse section of a whole mount stained 10.5 dpc embryo. Znf131 transcripts are detected in the neocortex and the hindbrain (hb) region of the prospective cerebellum (prc). (sv): Telencephalic vesicle forming the second ventricle, (tv): third ventricle, (fv): fourth ventricle, (pp): prospective pons. (H) Transverse section in a more caudal region. Staining is visible especially in the neuroepithelium (ne) (ine: inner neuroepithelium) of the neural tube (nt) and in the fore limb (fl).
Expression Pattern Description
Spatial Annotation:
EMAGE:5361Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5361_wholemount__moderate.wlz
5361_wholemount__weak.wlz
5361_wholemount__notDetected.wlz
5361_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5361_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
future forebrain
detected detected
future midbrain
detected detected
regionalExpressed in rostral apical midbrain.
neural tube
detected detected
regionalStaining is visible especially in the neuroepithelium (ne) (ine: inner neuroepithelium) of the neural tube.
forelimb bud
detected detected
hindlimb bud
detected detected
telencephalic vesicle
detected detected
regional
3rd ventricle
detected detected
regional
mesencephalic vesicle
detected detected
regional
future hindbrain
detected detected
regionalStaining is detected especially in the neural fold (nf) of the prospective hindbrain (phb)
4th ventricle
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Zfp131 probeA
Entity Detected:Zfp131, zinc finger protein 131 ( MGI:1919715)
Sequence:sense strand is shown

>Zfp131 probeA
CAGGACCGGTTTACGGACATCACCCTGATTGTCGACGGACACCATTTTAAGGCCCACAAGGCTGTTTTGG
CTGCCTGCAGTAAGTTCTTCTACAAATTCTTCCAGGAGTTTACTCAAGAGCCTTTGGTTGAAATTGAAGG
TGTTAGTAAAATGGCTTTTCGCCACTTAATTGAGTTCACATACACAGCAAAACTAATGATACAAGGGGAA
GAAGAAGCCAATGATGTGTGGAAAGCAGCAGAGTTTCTACAAATGCTGGAAGCTATTAAAGCACTTGAAG
TCAGGAACAAAGAAAACTCAGCTCCATTAGAGGAAAACACTACAGGAAAAAATGAGGCAAAAAAAAGAAA
GATTGCAGAAACTTCAAATGTTATCACTGAATCATTACCATCTGCAGAATCAGAACCTGTGGAAATTGAG
GTGGAGATTGCTGAGGGCACAATTGAAGTAGAAGATGAAGGCATCGAAGCTTTGGAGGAAATGGCTTCTG
CCAAGCAGTCTATAAAGTACATACAGAGCACAGGCTCCTCCGATGATTCCGCTCTGGCGTTGTTGGCAGA
TATCACCAGCAAGTACCGTCAAGGTGAAAGCAAAGGACAGATTAGCGAAGATGACTGTGCATCTGACCCC
ATAAGCAAACAGGTAGAAGGTATTGAAATTGTGGAACTTCAGCTGTCACATGTGAAGGACTTGTTCCATT
GTGAGAAATGTAACCGTTCATTTAAATTGTTTTACCATTTTAAGGAACACATGAAATCACACTCCACTGA
GAGTTTCAAGTGTGAAATATGCAATAAAAGGTATCTTCGAGAGAGTGCGTGGAAACAGCACCTAAACTGT
TACCACCTTGAAGAAGGTGGAGTAAGTAAGAAGCAAAGAACTGGGAAAAAAATTCACATATGCCAGTACT
GTGACAAACAGTTTGACCACTTTGGACACTTTAAAGAACACCTTCGAAAACATACAGGTGAAAAACCTTT
TGAATGTTCAAATTGTCACGAGCGGTTTGCTAGAAATAGCACTCTCAAATGTCACCTCACTGCATGCCAA
ACTGGAGTAGGAGCAAAAAAGGGCAGGAAGAAGCTTTATGAATGCCAGGTCTGTAACAGTGTATTTAACA
GCTGGGACCAGTTCAAAGATCA
nt 224 - nt 1365 of AY092766.1
Notes:The Zfp131 (Znf131) probe used in this study by Trappe et al., 2002 [PMID:12163020] was a "1142-bp murine Znf131 cDNA fragment from the 5'-region (nucleotide position 224-1365 of the cDNA sequence)" Editors Note: Elsewhere, Trappe et al refer to the identifer of their reported cDNA sequence as AY092766.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:C57BL/6J
Age:10.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Trappe R; Buddenberg P; Uedelhoven J; Glaser B; Buck A; Engel W; Burfeind P, 2002 [PMID:12163020] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0006-291X(02)00850-1] [ PMID:12163020] Trappe R, Buddenberg P, Uedelhoven J, Gl�ser B, Buck A, Engel W, Burfeind P 2002 The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus. Biochem Biophys Res Commun (296):319-27
Links: Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE