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EMAGE:539

Tlx2 T-cell leukemia, homeobox 2 ( MGI:1350935)
TS08 (6.5 dpc)
in situ hybridisation

Data Images
EMAGE:539
Fig 1A, Tang et al, 1998 [PMID:9550720] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
This embryo has no detectable Tlx2 expression. Expression is first noted in the primitive streak when it appears.
Expression Pattern Description
Spatial Annotation:
EMAGE:539Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
539_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:539_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
not detected not detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1276508
Entity Detected:Tlx2, T-cell leukemia, homeobox 2 ( MGI:1350935)
Notes:Two Tlx2 probes were used in this study by Tang et al, 1998 [PMID:9550720] , both of which are of unspecified sequence and both of which "yielded the same expression pattern, whereas the corresponding sense probes did not produce specific signals".
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:6.5 dpc
Theiler Stage:TS08
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Tang et al, 1998 [PMID:9550720] . Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9550720] Tang SJ, Hoodless PA, Lu Z, Breitman ML, McInnes RR, Wrana JL, Buchwald M 1998 The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development (125):1877-87
Links:MGI:1316852 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI