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EMAGE:570

Smad1 MAD homolog 1 (Drosophila) ( MGI:109452)
TS09 (6.5 dpc)
in situ hybridisation

Data Images
EMAGE:570 EMAGE:570
Figure 6A' of Tremblay et al., 2001 [PMID:11566864] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright. Figure 6A of Tremblay et al., 2001 [PMID:11566864] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: no stars
Notes:
Corresponding bright and darkfield images are shown below. Abbreviations used: ec, ectoderm; ep, epiblast; ve, visceral endoderm.
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
visceral extraembryonic endoderm
strong strong
primitive streak
strong strong
embryo
weak weak
regionalAuthors state expression is low in the early epiblast
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2155348
Entity Detected:Smad1, MAD homolog 1 (Drosophila) ( MGI:109452)
Notes:The Madh1 (Smad1) probe used in this study by Tremblay et al., 2001 [PMID:11566864] is indicated as being described by Waldrip et al., 1998 [PMID:9529255] ie. as a "full-length cDNA". Exact end positions are not specified.
Chemistry:RNA
Strand:antisense
Label:Unspecified radioactivity
Specimen
Organism:mouse
Strain:MF1
Age:6.5 dpc
Theiler Stage:TS09
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
Embedding:paraffin
Staining procedure:autoradiography
General Information
Authors:Tremblay et al., 2001 [PMID:11566864] . Indexed by GXD.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0092-8674(00)81407-5] [ PMID:9529255] Waldrip WR, Bikoff EK, Hoodless PA, Wrana JL, Robertson EJ 1998 Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell (92):797-808
 [ PMID:11566864] Tremblay KD, Dunn NR, Robertson EJ 2001 Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development (128):3609-21
Links:MGI:2155958 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI