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EMAGE:5772

Hif1a hypoxia inducible factor 1, alpha subunit ( MGI:106918)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5772
Figure 7A. Copyright: This image is from Ema M; Taya S; Yokotani N; Sogawa K; Matsuda Y; Fujii-Kuriyama Y, Proc Natl Acad Sci U S A 1997 Apr 29;94(9):4273-8. [PMID:9113979] Copyright 1997 National Academy of Sciences, U.S.A.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: *, nonspecific signal in the otic vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:5772Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5772_wholemount__moderate.wlz
5772_wholemount__weak.wlz
5772_wholemount__notDetected.wlz
5772_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5772_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
cardiovascular system
weak weak
regionalHybridization signal was seen weakly in the vascular system
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Hif1a probeA
Entity Detected:Hif1a, hypoxia inducible factor 1, alpha subunit ( MGI:106918)
Notes:The Hif1a (mHIF1-alpha) probe used in this study by Ema et al., 1997 [PMID:9113979] is described by the authors as a "mHIF1-alpha probe (nucleotides 2514-3365)". Editors note: The authors do not refer these co-ordinates to a particular sequence therefore the region covered is unknown.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ema M; Taya S; Yokotani N; Sogawa K; Matsuda Y; Fujii-Kuriyama Y, 1997 [PMID:9113979] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1073/pnas.94.9.4273] [ PMID:9113979] Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y 1997 A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A (94):4273-8
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE