Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:5774

Hipk2 homeodomain interacting protein kinase 2 ( MGI:1314872)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5774 EMAGE:5774 EMAGE:5774 EMAGE:5774 EMAGE:5774
Figure 1A of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006. Figure 1B of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006. Figure 1C of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006. Figure 1D of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006. Figure 1E of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006.
EMAGE:5774
Figure 1F of [doi:10.1128/MCB.26.7.2758-2771.2006] Mol Cell Biol 2006 26: 2758-71 [PMID:11238884] Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2006.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: C-F in Figure 1A indicate section planes for Figures 1C-D. B is a dorsal view of the embryo in A. midbrain (mb); hindbrain (hb); oropharynx (or); first branchial arch (ba); otic vesicle (ov).
Expression Pattern Description
Spatial Annotation:
EMAGE:5774Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5774_wholemount__moderate.wlz
5774_wholemount__strong.wlz
5774_wholemount__notDetected.wlz
5774_wholemount__possible.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5774_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
nervous system
strong strong
future midbrain
strong strong
future hindbrain
strong strong
optic vesicle
strong strong
otocyst
strong strong
Expression was intense in the region juxtaposed to the surface ectoderm.
mesenchyme derived from head mesoderm
weak weak
Expression was weaker in mesodermal tissue in the cranial region.
pharynx
detected detected
regionalExpression was detected in the oropharynx.
1st branchial arch
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3624089
Entity Detected:Hipk2, homeodomain interacting protein kinase 2 ( MGI:1314872)
Notes:The Hipk2 probe used in this study by Isono et al., 2006 [PMID:16537918] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Isono K; Nemoto K; Li Y; Takada Y; Suzuki R; Katsuki M; Nakagawara A; Koseki H, 2006 [PMID:16537918] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1128/MCB.26.7.2758-2771.2006] [ PMID:16537918] Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, Katsuki M, Nakagawara A, Koseki H 2006 Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol (26):2758-71
Links:MGI:3624104 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI