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EMAGE:578

Sox9 SRY-box containing gene 9 ( MGI:98371)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:578
Figure 4G of Lettice et al., 1999 [PMID:10518490] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrowhead indicates fibula; arrow indicates tibia.
Expression Pattern Description
Spatial Annotation:
EMAGE:578Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
578_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:578_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
footplate mesenchyme
detected detected
regionalExpression marks the condensing mesenchyme that will form the skeletal elements.
future leg mesenchyme
detected detected
regionalExpression marks the condensing mesenchyme that will form the skeletal elements.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1346803
Entity Detected:Sox9, SRY-box containing gene 9 ( MGI:98371)
Notes:The Sox9 probe used in this study by Lettice et al., 1999 [PMID:10518490] was a gift from R.Lovell-Badge and is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:C57BL/6
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase
General Information
Authors:Lettice et al., 1999 [PMID:10518490] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10518490] Lettice L, Hecksher-Sorensen J, Hill RE 1999 The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs. Development (126):4729-36
Links:MGI:1347778 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI