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EMAGE:5787

Hoxc11 homeobox C11 ( MGI:96193)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5787
Figure 3A. of [doi:10.1016/S0925-4773(97)00182-2] Copyright: Reprinted with permission from Elsevier from Mech Dev 70: 133-45, Hostikka SL; Capecchi MR, "The mouse Hoxc11 gene: genomic structure and expression pattern." Copyright 1998. [PMID:9510030]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5787Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5787_wholemount__moderate.wlz
5787_wholemount__possible.wlz
5787_wholemount__notDetected.wlz
5787_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5787_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
hindlimb bud mesenchyme
detected detected
regionalHoxc11 expression is first seen in the posterior half of the hindlimb bud at approximately E10. Within this compartment the expression appears uniform throughout the mesenchyme.
tail mesenchyme
detected detected
regionalExpressed in the mesenchyme of the tailbud.
dorsal root ganglion
detected detected
axial skeleton
detected detected
Expressed in 'prevertebrae'
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Hoxc11 probeA
Entity Detected:Hoxc11, homeobox C11 ( MGI:96193)
Notes:The Hoxc11 probe used in this study by Hostikka & Capecchi, 1998 [PMID:9510030] was either "a 420 bp Xba I-Acc I fragment from the 3' untranslated region" or "a subclone containing a 420 bp Eag I fragment from exon 1 extending 20 bp into the intron". The authors state that both probes gave identical results, and do not specify which was used in each experiment.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Hostikka SL & Capecchi MR, 1998 [PMID:9510030] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(97)00182-2] [ PMID:9510030] Hostikka SL, Capecchi MR 1998 The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev (70):133-45
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE