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EMAGE:5794

Id4 inhibitor of DNA binding 4 ( MGI:99414)
TS16 (10.5 dpc)
in situ reporter

Data Images
EMAGE:5794
Figure S1, 10.5 +/-. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/j.ydbio.2005.02.001] Dev Biol 280: 386-95, Bedford L; Walker R; Kondo T; van Cruchten I; King ER; Sablitzky F, "Id4 is required for the correct timing of neural differentiation." Copyright 2005 [PMID:15882580]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: FlB: forelimb bud, HlB: hindlimb bud, Ht: heart, IV: fourth ventricle, OV: otic vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:5794Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5794_wholemount__notDetected.wlz
5794_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5794_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalThe authors do not describe this expression pattern, however they state that "expression of the Id4/lacZ fusion gene was temporally and spatially similar to the endogenous Id4 gene expression".
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Id4, inhibitor of DNA binding 4 ( MGI:99414)
Notes:Id4 expression was revealed in this study by Bedford et al., 2005 [PMID:15882580] in a heterozygote for a targeted allele where a lacZ-neo cassette replaced sequence encoding the HLH domain and most of the C-terminus of the gene. The cassette was inserted in-frame, allowing the expression of a fusion gene encoding the N-terminal 65 amino acids of Id4 fused to beta-galactosidase.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd * CD-1
Age:10.5 dpc
Theiler Stage:TS16
Mutations:Id4tm1Fsky/Id4+
Preparation:wholemount
Procedures
General Information
Authors:Bedford L; Walker R; Kondo T; van Cruchten I; King ER; Sablitzky F, 2005 [PMID:15882580] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ydbio.2005.02.001] [ PMID:15882580] Bedford L, Walker R, Kondo T, van Cr�chten I, King ER, Sablitzky F 2005 Id4 is required for the correct timing of neural differentiation. Dev Biol (280):386-95
Links:MGI:3579084 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE