EMAGE mouse gene expression spatial database

EMAGE:5795

Ift88 intraflagellar transport 88 homolog (Chlamydomonas) ( MGI:98715)
TS18 (10.5 dpc)
in situ reporter

Data Images


Figure 5D. [doi:10.1002/dvdy.10289] Copyright: This image is from Zhang Q; Murcia NS; Chittenden LR; Richards WG; Michaud EJ; Woychik RP; Yoder BK, "Loss of the Tg737 protein results in skeletal patterning defects." Dev Dyn 2003; 227: 78-90. Reprinted with permission of Wiley-Liss Inc. [PMID:12701101]

Expression pattern clarity:
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Notes:

The authors state this is a hind-limb bud. Image annotation: The anterior side of the limb bud is marked with an asterisk.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

wholemount mapping

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Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

limb

detected

homogeneous

Expressed throughout the limb bud with very low or no expression in the AER.

hindlimb bud apical ectodermal ridge

possible

homogeneous

Very low or no expression in the AER.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ reporter
Entity Detected:	Ift88, intraflagellar transport 88 homolog (Chlamydomonas) ( MGI:98715)
Notes:	Ift88 (Tg737) expression was revealed in this study by Zhang et al., 2003 [PMID:12701101] in mice heterozygous for a targeted allele that was originally described by Murcia et al, 2000 [PMID:10804177] , i.e. where a genomic fragment containing exons 2 and part of 3 was replaced with a lacZ gene with a splice acceptor site and neomycin selection cassette.
Labelled with:	LacZ

Specimen

Procedures

Fixation:

2% paraformaldehyde

General Information

Authors:	Zhang Q; Murcia NS; Chittenden LR; Richards WG; Michaud EJ; Woychik RP; Yoder BK, 2003 [PMID:12701101] . Indexed and spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1002/dvdy.10289] [ PMID:12701101] Zhang Q, Murcia NS, Chittenden LR, Richards WG, Michaud EJ, Woychik RP, Yoder BK 2003 Loss of the Tg737 protein results in skeletal patterning defects. Dev Dyn (227):78-90
	[ PMID:10804177] Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, Woychik RP 2000 The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development (127):2347-55
Links:	MGI:1859153 allele description
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source