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EMAGE:5800

Ilk integrin linked kinase ( MGI:1195267)
TS17 (10.5 dpc)
in situ reporter

Data Images
EMAGE:5800
Fig1B. [doi:10.1038/sj.embor.embor801] Grashoff C; Aszodi A; Sakai T; Hunziker EB; Fassler R. EMBO Rep 2003 Apr;4(4):432-8. "Integrin-linked kinase regulates chondrocyte shape and proliferation." [PMID:12671688] © Nature Publishing Group. Reproduced with permission from EMBO Rep.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: h, heart; s, somite. Scale bar, 500 um.
Expression Pattern Description
Spatial Annotation:
EMAGE:5800Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5800_wholemount__moderate.wlz
5800_wholemount__possible.wlz
5800_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5800_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
trunk somite
strong strong
heart
strong strong
embryo
detected detected
The authors state that at E10.5, the embryo showed "strong expression in the somites and in the heart, and lower levels of expression in other tissues".
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Ilk, integrin linked kinase ( MGI:1195267)
Notes:Ilk expression was revealed in this study by Grashoff et al., 2003 [PMID:12671688] in an embryo heterozygous for a targeted allele where the gene was disrupted by replacement of exon 2 with a lacZ-PGK-neo cassette.
Labelled with:LacZ
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:Ilktm1Ref/Ilk+
Preparation:wholemount
Procedures
General Information
Authors:Grashoff C; Aszodi A; Sakai T; Hunziker EB; Fassler R, 2003 [PMID:12671688] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/sj.embor.embor801] [ PMID:12671688] Grashoff C, Asz�di A, Sakai T, Hunziker EB, F�ssler R 2003 Integrin-linked kinase regulates chondrocyte shape and proliferation. EMBO Rep (4):432-8
Links:MGI:2655773 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE