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EMAGE:5807

Kdr kinase insert domain protein receptor ( MGI:96683)
TS16 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5807
Figure 3B. Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(01)00289-1] Mech Dev 102: 205-8, Ayadi A; Suelves M; Dolle P; Wasylyk B, "Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development." Copyright 2001. [PMID:11287193]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: ao, aorta; isv, intersomitic vessels; uv, umbilical vein.
Expression Pattern Description
Spatial Annotation:
EMAGE:5807Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5807_wholemount__moderate.wlz
5807_wholemount__weak.wlz
5807_wholemount__possible.wlz
5807_wholemount__notDetected.wlz
5807_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5807_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
cardiovascular system
detected detected
regionalExpressed in the aorta, umbilical vein, intersomitic vessels, and head and neck vessels, intersomitic vessels, large blood vessels of the head and in the small capillary network of the developing brain and eye.
branchial arch
detected detected
regionalExpressed in mesenchyme.
forelimb bud mesenchyme
detected detected
hindlimb bud mesenchyme
detected detected
frontal process mesenchyme
detected detected
latero-nasal process mesenchyme
detected detected
medial-nasal process mesenchyme
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Kdr probeA
Entity Detected:Kdr, kinase insert domain protein receptor ( MGI:96683)
Sequence:sense strand is shown

>Kdr probeA
TGACTGAATGCGGCGGTGGTGACAGTATCTTCTGCAAAACACTCACCATTCCCAGGGTGGTTGGAAATGA
TACTGGAGCCTACAAGTGCTCGTACCGGGACGTCGACATAGCCTCCACTGTTTATGTCTATGTTCGAGAT
TACAGATCACCATTCATCGCCTCTGTCAGTGACCAGCATGGCATCGTGTACATCACCGAGAACAAGAACA
AAACTGTGGTGATCCCCTGCCGAGGGTCGATTTCAAACCTCAATGTGTCTCTTTGCGCTAGGTATCCAGA
AAAGAGATTTGTTCCGGATGGAAACAGAATTTCCTGGGACAGCGAGATAGGCTTTACTCTCCCCAGTTAC
ATGATCAGCTATGCCGGCATGGTCTTCTGTGAGGCAAAGATCAATGATGAAACCTATCAGTCTATCATGT
ACATAGTTGTGGTTGTAGGATATAGGATTTATGATGTGATTCTGAGCCCCCCGCATGAAATTGAGCTATC
TGCCGGAGAAAAACTTGTCTTAAATTGTACAGCGAGAACAGAGCTCAATGTGGGGCTTGATTTCACCTGG
CACTCTCCACCTTCAAAGTCTCATCATAAGAAGATTGTAAACCGGGATGTGAAACCCTTTCCTGGGACTG
TGGCGAAGATGTTTTTGAGCACCTTGACAATAGAAAGTGTGACCAAGAGTGACCAAGGGGAATACACCTG
TGTAGCGTCCAGTGGACGGATGATCAAGAGAAATAGAACATTTGTCCGAGTTCACACAAAGCCTTTTATT
GCTTTCGGTAGTGGGATGAAATCTTTGGTGGAAGCCACAGTGGGCAGTCAAGTCCGAATCCCTGTGAAGT
ATCTCAGTTACCCAGCTCCTGATATCAAATGGTACAGAAATGGAAGGCCCATTGAGTCCAACTACACAAT
GATTGTTGGCGATGAACTCACCATCATGGAAGTGACTGAAAGAGATGCAGGAAACTACACGGTCATCCTC
ACCAACCCCATTTCAATGGAGAAACAGAGCCACATGGTCTCTCTGGTTGTGAATGTCCCACCCCAGATCG
GTGAGAAAGCCTTGATCTCGCCTATGGATTCCTACCAGTATGGGACCATGCAGACATTGACATGCACAGT
CTACGCCAACCCTCCCCTGCACCACATCCAGTGGTACTGGCAGCTAGAAGAAGCCTGCTCCTACAGACCC
GGCCAAACAAGCCCGTATGCTTGTAAAGAATGGAGACACGTGGAGGATTTCCAGGGGGGAAACAAGATCG
AAGTCACCAAAAACCAATATGCCCTGATTGAAGGAAAAAACAAAACTGTAAGTACGCTGGTCATCCAAGC
TGCCAACGTGTCAGCGTTGTACAAATGTGAAGC
nt 512 - nt 1874 of X70842.1
Notes:The Kdr (Vegf-r2) probe used in this study by Ayadi et al., 2001 [PMID:11287193] PCR amplified "from a mouse lung cDNA Marathon-Ready library, Clontech; nucleotides 512-1874; Millauer et al., 1993 [PMID:7681362] ". Editor's note: Millauer made a direct submission to GenBank with the sequence X70842.1.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ayadi A; Suelves M; Dolle P; Wasylyk B, 2001 [PMID:11287193] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(01)00289-1] [ PMID:11287193] Ayadi A, Suelves M, Doll� P, Wasylyk B 2001 Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev (102):205-8
 [ doi:10.1016/0092-8674(93)90573-9] [ PMID:7681362] Millauer B, Wizigmann-Voos S, Schn�rch H, Martinez R, M�ller NP, Risau W, Ullrich A 1993 High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell (72):835-46
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE