EMAGE mouse gene expression spatial database

EMAGE:5817

Fosl1 fos-like antigen 1 ( MGI:107179)
TS17 (10.5 dpc)
in situ reporter

Data Images


Fig 2J. Copyright: This image is from Schreiber M; Wang Z; Jochum W; Fetka I; Elliott C; Wagner EF, Development 2000;127(22):4937-48 and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:11044407]	Fig 2I. Copyright: This image is from Schreiber M; Wang Z; Jochum W; Fetka I; Elliott C; Wagner EF, Development 2000;127(22):4937-48 and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:11044407]

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Fig2I is a wild-type embryo and is shown as a control.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

wholemount mapping

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Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

embryo

detected

Expression is widespread at E10.5, and apparently not restricted to specific organ systems.

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ reporter
Entity Detected:	Fosl1, fos-like antigen 1 ( MGI:107179)
Notes:	Fosl1 (Fra-1) expression was detected in this study by Schreiber et al., 2000 [PMID:11044407] in embryos with a targeted allelein which part of exon 3, all of intron 3, and part of exon 4 were replaced with a lacZ-neo derived cassette via homologous recombination, fusing lacZ in-frame with exon 3. The gene targeting event deletes most of the DNA-binding domain, the leucine zipper dimerization domain, and the last splice acceptor site.
Labelled with:	LacZ

Specimen

Procedures

Fixation:

4% paraformaldehyde

General Information

Authors:	Schreiber M; Wang Z; Jochum W; Fetka I; Elliott C; Wagner EF, 2000 [PMID:11044407] , Indexed and Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ PMID:11044407] Schreiber M, Wang ZQ, Jochum W, Fetka I, Elliott C, Wagner EF 2000 Placental vascularisation requires the AP-1 component fra1. Development (127):4937-48
Links:	MGI:2385824 allele description
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source