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EMAGE:5821

Foxe1 forkhead box E1 ( MGI:1353500)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5821
Fig 10C. Copyright: This image is from Martinez Barbera JP; Clements M; Thomas P; Rodriguez T; Meloy D; Kioussis D; Beddington RS, Development 2000;127(11):2433-45 and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:10804184]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrowhead indicates first branchial arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:5821Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5821_wholemount__moderate.wlz
5821_wholemount__notDetected.wlz
5821_wholemount__strong.wlz
5821_wholemount__possible.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5821_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
thyroid primordium
detected detected
foregut
detected detected
regionalFoxe1 is expressed in the thyroid primordium, most of the anterior foregut endoderm and oral ectoderm in wild-type 9.5 dpc embryos.
oral region
detected detected
regionalFoxe1 is expressed in the thyroid primordium, most of the anterior foregut endoderm and oral ectoderm in wild-type 9.5 dpc embryos.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Foxe1 probeA
Entity Detected:Foxe1, forkhead box E1 ( MGI:1353500)
Notes:The Foxe1 (TTF2) probe used in this study by Martinez Barbera et al., 2000 [PMID:10804184] is indicated as that previously described by Zannini et al., 1997 [PMID:9214635] i.e.: "a mouse TTF-2 RNA probe was synthetically produced using a 350 bp long fragment derived from the 3'-UTR of the cDNA subcloned in Bluescript."
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Martinez Barbera JP; Clements M; Thomas P; Rodriguez T; Meloy D; Kioussis D; Beddington RS, 2000 [PMID:10804184] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10804184] Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS 2000 The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development (127):2433-45
 [ doi:10.1093/emboj/16.11.3185] [ PMID:9214635] Zannini M, Avantaggiato V, Biffali E, Arnone MI, Sato K, Pischetola M, Taylor BA, Phillips SJ, Simeone A, Di Lauro R 1997 TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation. EMBO J (16):3185-97
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE