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EMAGE:5824

Foxi1 forkhead box I1 ( MGI:1096329)
TS19 (11.5 dpc)
in situ hybridisation

Data Images
EMAGE:5824
Fig3. Copyright: This image is from Hulander M; Kiernan AE; Blomqvist SR; Carlsson P; Samuelsson EJ; Johansson BR; Steel KP; Enerback S, Development 2003;130(9):2013-25 [doi:10.1242/dev.00376] and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:12642503]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Foxi1 has an otic vesicle-specific expression pattern (left panel, red arrowhead). At higher magnification (right panel), the contours of the future endolymphatic duct can be seen (arrowheads). Scale bars: 100 um.
Expression Pattern Description
Spatial Annotation:
EMAGE:5824Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5824_wholemount__moderate.wlz
5824_wholemount__notDetected.wlz
5824_wholemount__strong.wlz
5824_wholemount__weak.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5824_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
inner ear
detected detected
regionalFoxi1 expression is restricted to the otocyst with most of the staining in structures that will give rise to the endolymphatic duct and sac.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Foxi1 probeA
Entity Detected:Foxi1, forkhead box I1 ( MGI:1096329)
Notes:The Foxi1 probe used in this study by Hulander et al., 2003 [PMID:12642503] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:11.5 dpc
Theiler Stage:TS19
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Hulander M; Kiernan AE; Blomqvist SR; Carlsson P; Samuelsson EJ; Johansson BR; Steel KP; Enerback S, 2003 [PMID:12642503] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00376] [ PMID:12642503] Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S 2003 Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development (130):2013-25
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE