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EMAGE:5827

Frat1 frequently rearranged in advanced T-cell lymphomas ( MGI:109450)
TS19 (12.5 dpc)
in situ reporter

Data Images
EMAGE:5827
Fig 2B Copyright: Reprinted with permission from Elsevier from [doi:10.1016/S0925-4773(99)00187-2] Mech Dev 88: 183-94, Jonkers J; van Amerongen R; van der Valk M; Robanus-Maandag E; Molenaar M; Destree O; Berns A, In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3 Copyright 1999. [PMID:10534617]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5827Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5827_wholemount__moderate.wlz
5827_wholemount__weak.wlz
5827_wholemount__possible.wlz
5827_wholemount__notDetected.wlz
5827_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5827_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
strong strong
Strongest expression is in telencephalon, spinal cord, eye, and nasal pit.
future spinal cord
strong strong
Strongest expression is in telencephalon, spinal cord, eye, and nasal pit.
eye
strong strong
Strongest expression is in telencephalon, spinal cord, eye, and nasal pit.
olfactory pit
strong strong
Strongest expression is in telencephalon, spinal cord, eye, and nasal pit.
brain
detected detected
spinal ganglion
detected detected
handplate apical ectodermal ridge
detected detected
footplate apical ectodermal ridge
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Frat1, frequently rearranged in advanced T-cell lymphomas ( MGI:109450)
Notes:Frat1 expression was detected in this study by Jonkers et al., 1999 [PMID:10534617] in an embryo heterozygous for a targeted allele where 660 nucleotides of the coding region was replaced by the insertion of a cassette containing a lacZ beta-galactosidase gene and hygromycin selection gene.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:either: (involves: 129P/Ola * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB)
Age:12.5 dpc
Theiler Stage:TS19
Mutations:Frat1tm1Brn/Frat1+
Preparation:wholemount
Procedures
General Information
Authors:Jonkers J, van Amerongen R, van der Valk M, Robanus-Maandag E, Molenaar M, Destree O, Berns A, 1999 [PMID:10534617] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/S0925-4773(99)00187-2] [ PMID:10534617] Jonkers J, van Amerongen R, van der Valk M, Robanus-Maandag E, Molenaar M, Destree O, Berns A 1999 In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3. Mech Dev (1999):183-94
Links:MGI:2384128 allele description
 MGI:2686894 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE