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EMAGE:5837

Fth1 ferritin heavy chain 1 ( MGI:95588)
TS15 (9.5 dpc)
in situ reporter

Data Images
EMAGE:5837
Fig4(2). from J Biol Chem 2000 275(5): 3021-4, Ferreira C; Bucchini D; Martin ME; Levi S; Arosio P; Grandchamp B; Beaumont C, Early embryonic lethality of H ferritin gene deletion in mice. Copyright 2000 [PMID:10652280]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5837Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5837_wholemount__moderate.wlz
5837_wholemount__weak.wlz
5837_wholemount__possible.wlz
5837_wholemount__notDetected.wlz
5837_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5837_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
central nervous system
weak weak
X-gal staining was low, but easily detectable after 3 h of incubation, mostly in the developing heart and in the central nervous system. A longer incubation period did not noticeably change the pattern of expression.
heart
weak weak
X-gal staining was low, but easily detectable after 3 h of incubation, mostly in the developing heart and in the central nervous system. A longer incubation period did not noticeably change the pattern of expression.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Fth1, ferritin heavy chain 1 ( MGI:95588)
Notes:Fth1 (H-Ft) expression was assayed in this study by Ferreira et al., 2000 [PMID:10652280] in embryos heterozygous for a targeted allele where the last half of exon 2 and part of intron 2 were replaced with a promoterless IRES-betageo cassette via homologous recombination.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129S2/SvPas * C57BL/6
Age:9.5 dpc
Theiler Stage:TS15
Mutations:Fth1tm1Cbea/Fth1+
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Ferreira C; Bucchini D; Martin ME; Levi S; Arosio P; Grandchamp B; Beaumont C, 2000 [PMID:10652280] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1074/jbc.275.5.3021] [ PMID:10652280] Ferreira C, Bucchini D, Martin ME, Levi S, Arosio P, Grandchamp B, Beaumont C 2000 Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem (275):3021-4
Links:MGI:2386942 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE