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EMAGE:588

Sox3 SRY-box containing gene 3 ( MGI:98365)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:588
Figure 6D of Collignon et al., 1996 [PMID:8625802] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotations: f - forebrain; ot, otic vesicle; m, midbrain; h, hindbrain.
Expression Pattern Description
Spatial Annotation:
EMAGE:588EMAGE:588Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
588_voxel_strong_3D_1.wlz
588_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:588_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
future forebrain
detected detected
regionalExpression throughout the neuroectoderm.
optic vesicle
detected detected
gradedThe optic vesicles show a gradient of expression with the lowest levels distally.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1928758
Entity Detected:Sox3, SRY-box containing gene 3 ( MGI:98365)
Notes:The Sox3 probe used in this study by Collignon et al., 1996 [PMID:8625802] was described as follows. "Two probes from the 5' region of the Sox-3 gene were used: a 100-bp EcoRI-PstI fragment from the cDNA (position 1-108 on cDNA) and a 440-bp XhoI-XmnI fragment from the genomic clone." Not stipulated which was used here (the other is MGI:1928759).
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Collignon et al., 1996 [PMID:8625802] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:8625802] Collignon J, Sockanathan S, Hacker A, Cohen-Tannoudji M, Norris D, Rastan S, Stevanovic M, Goodfellow PN, Lovell-Badge R 1996 A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. Development (122):509-20
Links:MGI:1929458 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI