EMAGE mouse gene expression spatial database

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EMAGE:5923

Map1lc3a microtubule-associated protein 1 light chain 3 alpha ( MGI:1915661)
TS19 (11.5 dpc)
in situ hybridisation

Data Images


Figure 1B. This image is from [doi:10.1002/dvdy.21392] Cann GM; Guignabert C; Ying L; Deshpande N; Bekker JM; Wang L; Zhou B; Rabinovitch M, "Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice." Dev Dyn 2008; 237: 187-95. [PMID:18069693]	Figure 1A. This image is from [doi:10.1002/dvdy.21392] Cann GM; Guignabert C; Ying L; Deshpande N; Bekker JM; Wang L; Zhou B; Rabinovitch M, "Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice." Dev Dyn 2008; 237: 187-95. [PMID:18069693]	Figure 1C. This image is from [doi:10.1002/dvdy.21392] Cann GM; Guignabert C; Ying L; Deshpande N; Bekker JM; Wang L; Zhou B; Rabinovitch M, "Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice." Dev Dyn 2008; 237: 187-95. [PMID:18069693]

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

B and C show specimens hybridised with anti-sense probe. A shows a sense control. Image annotations: fb, forebrain; mb, midbrain; tg, trigeminal ganglia; ba, branchial arches; lb, limb bud; com, commissural neurons; drg, dorsal root ganglia, v, ventricles; ot, outflow tract.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

5923_wholemount__moderate.wlz

5923_wholemount__possible.wlz

5923_wholemount__notDetected.wlz

5923_wholemount__strong.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:5923_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

branchial arch

strong

forebrain

strong

midbrain

strong

trigeminal v ganglion

strong

dorsal root ganglion

strong

neural tube

strong

regional

Expression is in the commissural neurons in the dorsal neural tube.

limb

detected

outflow tract

detected

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	MGI:3776464
Entity Detected:	Map1lc3a, microtubule-associated protein 1 light chain 3 alpha ( MGI:1915661)
Notes:	The Map1lc3a (LC3 alpha) probe used in this study by Cann et al., 2008 [PMID:18069693] was a "pan LC3 antisense probe". Editor's note: The probe recognises both LC3 alpha and LC3 beta isoforms (Map1lc3a and Map1lc3b, respectively).
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	11.5 dpc
Theiler Stage:	TS19
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

General Information

Authors:	Cann GM; Guignabert C; Ying L; Deshpande N; Bekker JM; Wang L; Zhou B; Rabinovitch M, 2008 [PMID:18069693] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1002/dvdy.21392] [ PMID:18069693] Cann GM, Guignabert C, Ying L, Deshpande N, Bekker JM, Wang L, Zhou B, Rabinovitch M 2008 Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice. Dev Dyn (237):187-95
Links:	MGI:3776476 same experiment
	EMAGE:5924 same embryo
	EMAGE:5924 same probe
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source