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EMAGE:5940

Fkbp8 FK506 binding protein 8 ( MGI:1341070)
TS16 (10 dpc)
in situ hybridisation

Data Images
EMAGE:5940 EMAGE:5940
Fig3A (FKBP8 antisense). [doi:10.1242/dev.01122] Copyright: This image is from Bulgakov OV; Eggenschwiler JT; Hong DH; Anderson KV; Li T, Development 2004 May;131(9):2149-59 "FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues." and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:15105374] Fig3A (sense control). [doi:10.1242/dev.01122] Copyright: This image is from Bulgakov OV; Eggenschwiler JT; Hong DH; Anderson KV; Li T, Development 2004 May;131(9):2149-59 "FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues." and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:15105374]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Two specimens are shown, one hybridised with anti-sense probe and a control hybridised with sense probe.
Expression Pattern Description
Spatial Annotation:
EMAGE:5940Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5940_wholemount__moderate.wlz
5940_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5940_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
homogeneousFkbp8 mRNA was found uniformly distributed throughout the E9.5 embryo.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Fkbp8 probeA
Entity Detected:Fkbp8, FK506 binding protein 8 ( MGI:1341070)
Notes:The Fkbp8 probe used in this study by Bulgakov et al., 2004 [PMID:15105374] was transcribed from a "plasmid carrying mouse cDNA for Fkbp8". "Fkbp8 sense and antisense probes were generated from a cDNA clone covering the entire coding region".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Bulgakov OV; Eggenschwiler JT; Hong DH; Anderson KV; Li T, 2004 [PMID:15105374] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01122] [ PMID:15105374] Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV, Li T 2004 FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Development (131):2149-59
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE