Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:5947

Chrnd cholinergic receptor, nicotinic, delta polypeptide ( MGI:87893)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5947
Fig6A-Chrnd-E10.5. [doi:10.1016/j.ajhg.2007.11.006] Michalk A; Stricker S; Becker J; Rupps R; Pantzar T; Miertus J; Botta G; Naretto VG; Janetzki C; Yaqoob N; Ott CE; Seelow D; Wieczorek D; Fiebig B; Wirth B; Hoopmann M; Walther M; Korber F; Blankenburg M; Mundlos S; Heller R; Hoffmann K, "Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders." Am J Hum Genet 2008; 82: 464-76. [PMID:18252226]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5947Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5947_wholemount__moderate.wlz
5947_wholemount__weak.wlz
5947_wholemount__possible.wlz
5947_wholemount__notDetected.wlz
5947_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5947_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
trunk somite
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Chrnd probeA
Entity Detected:Chrnd, cholinergic receptor, nicotinic, delta polypeptide ( MGI:87893)
Notes:The Chrnd probe used in this study by Michalk et al., 2008 [PMID:18252226] was one of two probes either generated "by RT-PCR from mouse E14.5 whole cDNA" or received "from Bernhard Hermann and Heiner Schrewe (MPI for Molecular Genetics, Berlin)". Both are of unreported sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Michalk A; Stricker S; Becker J; Rupps R; Pantzar T; Miertus J; Botta G; Naretto VG; Janetzki C; Yaqoob N; Ott CE; Seelow D; Wieczorek D; Fiebig B; Wirth B; Hoopmann M; Walther M; Korber F; Blankenburg M; Mundlos S; Heller R; Hoffmann K, 2008 [PMID:18252226] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.ajhg.2007.11.006] [ PMID:18252226] Michalk A, Stricker S, Becker J, Rupps R, Pantzar T, Miertus J, Botta G, Naretto VG, Janetzki C, Yaqoob N, Ott CE, Seelow D, Wieczorek D, Fiebig B, Wirth B, Hoopmann M, Walther M, K�rber F, Blankenburg M, Mundlos S, Heller R, Hoffmann K 2008 Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders. Am J Hum Genet (82):464-76
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE