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EMAGE:5959

F11r F11 receptor ( MGI:1321398)
TS15 (9.5 dpc)
in situ reporter

Data Images
EMAGE:5959
Fig1G. [doi:10.1002/dvdy.20481] Copyright: This image is from Parris JJ; Cooke VG; Skarnes WC; Duncan MK; Naik UP, "JAM-A expression during embryonic development." Dev Dyn 2005; 233: 1517-24. Reprinted with permission of Wiley-Liss Inc. [PMID:15977176] .

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: isv, intersomitic vessels; op, otic pit/vesicle.
Expression Pattern Description
Spatial Annotation:
EMAGE:5959Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5959_wholemount__moderate.wlz
5959_wholemount__weak.wlz
5959_wholemount__notDetected.wlz
5959_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5959_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
embryo
detected detected
regionalExpression has decreased ventrally compared to earlier stages.
cardiovascular system
detected detected
regionalExpressed in the intersomitic vessels
otocyst
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:F11r, F11 receptor ( MGI:1321398)
Notes:F11r (JAM-A) expression was revealed in this study by Parris et al., 2005 [PMID:15977176] in embryos heterozygous for a gene trapped allele. In this allele, a gene trap vector (pGT1TMpfs) insertion resulted in the fusion of the first Ig domain to TMbetageo, an artificial protein created from the transmembrane domain of rat Cd4 joined to the catalytically active domains of betagalactosidase and neomycin genes followed by an IRES and placental alkaline phosphatase reporter cassette. The betagalactosidase and neomycin genes are flanked by Frt sites. The absence of protein product in the endothelium of the aorta was confirmed by immunohistochemistry.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129P2/OlaHsd * C57BL/6
Age:9.5 dpc
Theiler Stage:TS15
Mutations:F11rGt(KST235)Byg/F11r+
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Parris JJ; Cooke VG; Skarnes WC; Duncan MK; Naik UP, 2005 [PMID:15977176] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1002/dvdy.20481] [ PMID:15977176] Parris JJ, Cooke VG, Skarnes WC, Duncan MK, Naik UP 2005 JAM-A expression during embryonic development. Dev Dyn (233):1517-24
Links:MGI:3583782 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE