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EMAGE:5965

Foxl2 forkhead box L2 ( MGI:1349428)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5965
Fig2J. [doi:10.1242/dev.019778] Copyright: This image is from Jeong J; Li X; McEvilly RJ; Rosenfeld MG; Lufkin T; Rubenstein JL, "Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs." Development 2008; 135: 2905-16 and is displayed with the permission of The Company of Biologist Limited who owns the Copyright. [PMID:18697905]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: The arrow indicates a region of the mandibular part of branchial arch 1 where expression of Foxl2 is upregulated in Dlx5/6-/- mutant embryos. See Fig 2K in the manuscript for the accompanying image showing the mutant.
Expression Pattern Description
Spatial Annotation:
EMAGE:5965Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5965_wholemount__moderate.wlz
5965_wholemount__weak.wlz
5965_wholemount__notDetected.wlz
5965_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5965_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
1st branchial arch maxillary component
strong strong
regionalExpressed strongly in the dorsal maxillary branchial arch 1 just below the eye.
1st branchial arch maxillary-mandibular groove
strong strong
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Foxl2 probeA
Entity Detected:Foxl2, forkhead box L2 ( MGI:1349428)
Notes:The Foxl2 probe used in this study by Jeong et al., 2008 [PMID:18697905] was either "obtained by PCR from a wild-type mouse E10.5 BA1 (1st branchial arch) cDNA library or from adult tail genomic DNA", "purchased from (a) company", or "kindly provided by other investigators", it is not specified which. The probe is also of unreported identity and sequence
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Jeong J; Li X; McEvilly RJ; Rosenfeld MG; Lufkin T; Rubenstein JL, 2008 [PMID:18697905] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.019778] [ PMID:18697905] Jeong J, Li X, McEvilly RJ, Rosenfeld MG, Lufkin T, Rubenstein JL 2008 Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development (135):2905-16
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE