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EMAGE:5967

Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 ( MGI:1100842)
TS19 (11.5 dpc)
in situ reporter

Data Images
EMAGE:5967
Figure 1C. Copyright: Reprinted with permission from Cell Press from [doi:10.1016/j.neuron.2004.10.032] Neuron 44: 623-36, Enomoto H; Hughes I; Golden J; Baloh RH; Yonemura S; Heuckeroth RO; Johnson EM Jr; Milbrandt J, "GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration." Copyright 2004. [PMID:15541311]

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotation: arrow, ureteric bud.
Expression Pattern Description
Spatial Annotation:
EMAGE:5967Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5967_wholemount__moderate.wlz
5967_wholemount__weak.wlz
5967_wholemount__notDetected.wlz
5967_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5967_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
central nervous system nerve
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ reporter
Entity Detected:Gfra1, glial cell line derived neurotrophic factor family receptor alpha 1 ( MGI:1100842)
Notes:Gfra1 expression was assayed in this study by Enomoto et al., 2004 [PMID:15541311] in embryos heterozygous for a targeted allele where a tau-lacZ and neo cassette was inserted into the second exon deleting 95 bp of the 5' untranslated region including the start codon. The neo cassette was removed by germ-line, cre-mediated recombination. LacZ expression recapitulated endogenous promoter expression. Absence of target expression was confirmed by in situ hybridization. This is a null allele.
Labelled with:LacZ
Specimen
Organism:mouse
Strain:involves: 129X1/SvJ
Age:11.5 dpc
Theiler Stage:TS19
Mutations:Gfra1tm3Jmi/Gfra1+
Preparation:wholemount
Procedures
General Information
Authors:Enomoto H; Hughes I; Golden J; Baloh RH; Yonemura S; Heuckeroth RO; Johnson EM Jr; Milbrandt J, 2004 [PMID:15541311] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.neuron.2004.10.032] [ PMID:15541311] Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM, Milbrandt J 2004 GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron (44):623-36
Links:MGI:3774317 allele description
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE