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EMAGE:5979

Htra1 HtrA serine peptidase 1 ( MGI:1929076)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5979
Fig6I. [doi:10.1002/dvdy.21597] Copyright: This image is from Ferrer-Vaquer A; Maurey P; Werzowa J; Firnberg N; Leibbrandt A; Neubuser A, "Expression and regulation of HTRA1 during chick and early mouse development." Dev Dyn 2008; 237: 1893-900. Reprinted with permission of Wiley-Liss Inc. [PMID:18570253] .

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5979Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5979_wholemount__moderate.wlz
5979_wholemount__possible.wlz
5979_wholemount__strong.wlz
5979_wholemount__notDetected.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5979_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
dorsal aorta
detected detected
branchial arch artery
detected detected
endocardial cushion tissue
weak weak
notochord
detected detected
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Htra1 probeA
Entity Detected:Htra1, HtrA serine peptidase 1 ( MGI:1929076)
Notes:The Htra1 probe used in this study by Ferrer-Vaquer et al., 2008 [PMID:18570253] was kindly provided by Professor Masashi Kawaichi and is indicated as that described by Oka et al., 2004 [PMID:14973287] . Editors Note: Oka et al, describe two Htra1 in situ probes, both of which "gave identical results": either a "BalI-BamHI fragment (nucleotide 644-1191)" or "a BamHI-HincII fragment (nucleotide 1191-1750)". The nucleotide numbering refers to AF172994.1. Ferrer-Vaquer et al. do not indicate which of these two they used.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:NMRI
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Ferrer-Vaquer A; Maurey P; Werzowa J; Firnberg N; Leibbrandt A; Neubuser A, 2008 [PMID:18570253] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1002/dvdy.21597] [ PMID:18570253] Ferrer-Vaquer A, Maurey P, Werzowa J, Firnberg N, Leibbrandt A, Neub�ser A 2008 Expression and regulation of HTRA1 during chick and early mouse development. Dev Dyn (237):1893-900
 [ doi:10.1242/dev.00999] [ PMID:14973287] Oka C, Tsujimoto R, Kajikawa M, Koshiba-Takeuchi K, Ina J, Yano M, Tsuchiya A, Ueta Y, Soma A, Kanda H, Matsumoto M, Kawaichi M 2004 HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Development (131):1041-53
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE