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EMAGE:598

Sox17 SRY-box containing gene 17 ( MGI:107543)
TS11 (7.75 dpc)
in situ hybridisation

Data Images
EMAGE:598
Figure 1M of Kanai-Azuma et al., 2002 [PMID:11973269] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrow indicates the expanding zone of Sox17-expressing cells from previous stages. This embryo is also described by the authors as early neural plate stage.
Expression Pattern Description
Spatial Annotation:
EMAGE:598Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
598_wholemount_strong_3D_1.wlz
598_wholemount_moderate_3D_1.wlz
598_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:598_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
definitive endoderm
detected detected
regionalExpression is present in the endoderm of the prospective foregut.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2179830
Entity Detected:Sox17, SRY-box containing gene 17 ( MGI:107543)
Notes:The Sox17 probe used in this study by Kanai-Azuma et al., 2002 [PMID:11973269] is indicated as that previously described by Kanai et al., 1996 [PMID:8636240] ie. either "probe B (EcoRI-digested {+1750 to +2375} fragment of t-Sox17) or probe C (DNA fragment corresponding to the spliced exon {+564 to +863}) ". Not specified which is used here.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:7.75 dpc
Theiler Stage:TS11
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Kanai-Azuma et al., 2002 [PMID:11973269] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11973269] Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y 2002 Depletion of definitive gut endoderm in Sox17-null mutant mice. Development (129):2367-79
 [ doi:10.1083/jcb.133.3.667] [ PMID:8636240] Kanai Y, Kanai-Azuma M, Noce T, Saido TC, Shiroishi T, Hayashi Y, Yazaki K 1996 Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis. J Cell Biol (133):667-81
Links:MGI:2180010 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI