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EMAGE:5982

Igfbp4 insulin-like growth factor binding protein 4 ( MGI:96439)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:5982
FigS3H. [doi:10.1038/nature07027] Zhu W; Shiojima I; Ito Y; Li Z; Ikeda H; Yoshida M; Naito AT; Nishi J; Ueno H; Umezawa A; Minamino T; Nagai T; Kikuchi A; Asashima M; Komuro I, "IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis." Nature 2008; 454: 345-9. [PMID:18528331] © Nature Publishing Group. Reproduced with permission from Nature.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:5982Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5982_wholemount__moderate.wlz
5982_wholemount__possible.wlz
5982_wholemount__notDetected.wlz
5982_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5982_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
branchial arch
strong strong
limb
strong strong
biliary bud
strong strong
Strong signals detected in liver bud
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Igfbp4 probeA
Entity Detected:Igfbp4, insulin-like growth factor binding protein 4 ( MGI:96439)
Notes:The Igfbp4 probe used in this study by Zhu et al., 2008 [PMID:18528331] is of unreported sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Zhu W; Shiojima I; Ito Y; Li Z; Ikeda H; Yoshida M; Naito AT; Nishi J; Ueno H; Umezawa A; Minamino T; Nagai T; Kikuchi A; Asashima M; Komuro I, 2008 [PMID:18528331] . Indexed and spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/nature07027] [ PMID:18528331] Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I 2008 IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. Nature (454):345-9
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE