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EMAGE:5985

Iqcb1 IQ calmodulin-binding motif containing 1 ( MGI:2443764)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:5985 EMAGE:5985
Figure S2D. [doi:10.1038/ng1520] Otto EA; Loeys B; Khanna H; Hellemans J; Sudbrak R; Fan S; Muerb U; O'Toole JF; Helou J; Attanasio M; Utsch B; Sayer JA; Lillo C; Jimeno D; Coucke P; De Paepe A; Reinhardt R; Klages S; Tsuda M; Kawakami I; Kusakabe T; Omran H; Imm A; Tippens M; Raymond PA; Hill J; Beales P; He S; Kispert A; Margolis B; Williams DS; Swaroop A; Hildebrandt F, "Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin." Nat Genet 2005; 37: 282-8. [PMID:15723066] © Nature Publishing Group. Reproduced with permission from Nat Genet. Figure S2F. [doi:10.1038/ng1520] Otto EA; Loeys B; Khanna H; Hellemans J; Sudbrak R; Fan S; Muerb U; O'Toole JF; Helou J; Attanasio M; Utsch B; Sayer JA; Lillo C; Jimeno D; Coucke P; De Paepe A; Reinhardt R; Klages S; Tsuda M; Kawakami I; Kusakabe T; Omran H; Imm A; Tippens M; Raymond PA; Hill J; Beales P; He S; Kispert A; Margolis B; Williams DS; Swaroop A; Hildebrandt F, "Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin." Nat Genet 2005; 37: 282-8. [PMID:15723066] © Nature Publishing Group. Reproduced with permission from Nat Genet.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
d - hybridised with antisense probe. f - hybridised with sense probe.
Expression Pattern Description
Spatial Annotation:
EMAGE:5985Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
5985_wholemount__moderate.wlz
5985_wholemount__weak.wlz
5985_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:5985_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
embryo
weak weak
Expressed ubiquitously.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3783661
Entity Detected:Iqcb1, IQ calmodulin-binding motif containing 1 ( MGI:2443764)
Notes:The Iqcb1 probe used in this study by Otto et al., 2005 [PMID:15723066] was "generated from a 1.9-kb Iqcb1 mouse cDNA cloned in pCMVSport6 using T7 RNA polymerase".
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Otto EA; Loeys B; Khanna H; Hellemans J; Sudbrak R; Fan S; Muerb U; O'Toole JF; Helou J; Attanasio M; Utsch B; Sayer JA; Lillo C; Jimeno D; Coucke P; De Paepe A; Reinhardt R; Klages S; Tsuda M; Kawakami I; Kusakabe T; Omran H; Imm A; Tippens M; Raymond PA; Hill J; Beales P; He S; Kispert A; Margolis B; Williams DS; Swaroop A; Hildebrandt F, 2005 [PMID:15723066] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1038/ng1520] [ PMID:15723066] Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F 2005 Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet (37):282-8
Links:MGI:3783670 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI