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EMAGE:6023

Mpzl2 myelin protein zero-like 2 ( MGI:1289160)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:6023 EMAGE:6023
Fig1A(9.5)top. [doi:10.1016/j.bbrc.2007.02.131] Reprinted from Biochem Biophys Res Comm, vol 356(2), DeMonte L; Porcellini S; Tafi E; Sheridan J; Gordon J; Depreter M; Blair N; Panigada M; Sanvito F; Merati B; Albientz A; Barthlott T; Ozmen L; Blackburn CC; Guttinger M, EVA regulates thymic stromal organisation and early thymocyte development. pp 334-40, Copyright (2007) with permission from Elsevier. [PMID:17362876] Fig1A(9.5)bottom. [doi:10.1016/j.bbrc.2007.02.131] Reprinted from Biochem Biophys Res Comm, vol 356(2), DeMonte L; Porcellini S; Tafi E; Sheridan J; Gordon J; Depreter M; Blair N; Panigada M; Sanvito F; Merati B; Albientz A; Barthlott T; Ozmen L; Blackburn CC; Guttinger M, EVA regulates thymic stromal organisation and early thymocyte development. pp 334-40, Copyright (2007) with permission from Elsevier. [PMID:17362876]

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations:TB, tail bud; H, heart; L, liver; FL, forelimb; HL, hindlimb; 1-3, pharyngeal arches; arrows indicate third pharyngeal pouch.
Expression Pattern Description
Spatial Annotation:
EMAGE:6023Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
6023_wholemount__moderate.wlz
6023_wholemount__possible.wlz
6023_wholemount__notDetected.wlz
6023_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:6023_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
branchial arch
detected detected
regionalEVA expression was first observed in the pharyngeal arch region at E9.5, in the pharyngeal pouches and pharyngeal endoderm.
tail
strong strong
regionalStrong expression was evident in ventral portion of the tail bud.
tail unsegmented mesenchyme
weak weak
biliary bud
strong strong
Strong expression was evident in the liver primordium
3rd branchial pouch
detected detected
EVA is expressed in the third pharyngeal pouches, that will generate the thymus
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Mpzl2 probeA
Entity Detected:Mpzl2, myelin protein zero-like 2 ( MGI:1289160)
Notes:The Mpzl2 (EVA) probe used in this study by DeMonte et al., 2007 [PMID:17362876] is described as "containing the full EVA coding region", however the exact sequence is not reported.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + unspecified
General Information
Authors:DeMonte L; Porcellini S; Tafi E; Sheridan J; Gordon J; Depreter M; Blair N; Panigada M; Sanvito F; Merati B; Albientz A; Barthlott T; Ozmen L; Blackburn CC; Guttinger M, 2007 [PMID:17362876] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.bbrc.2007.02.131] [ PMID:17362876] DeMonte L, Porcellini S, Tafi E, Sheridan J, Gordon J, Depreter M, Blair N, Panigada M, Sanvito F, Merati B, Albientz A, Barthlott T, Ozmen L, Blackburn CC, Guttinger M 2007 EVA regulates thymic stromal organisation and early thymocyte development. Biochem Biophys Res Commun (356):334-40
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE