EMAGE mouse gene expression spatial database

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EMAGE:6025

Mycbp2 MYC binding protein 2 ( MGI:2179432)
TS17 (10.5 dpc)
in situ hybridisation

Data Images


Fig3A of [doi:10.1128/MCB.24.3.1096-1105.2004] Mol Cell Biol 2004 24(3):1096-1105 [PMID:14729956] Burgess RW; Peterson KA; Johnson MJ; Roix JJ; Welsh IC; O'Brien TP, Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. � ASM. Reproduced with permission from Molecular and Cellular Biology. Reuse of any Licensed Material requires permission from ASM. Copyright 2004.

Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Notes:

Image annotations: fn, fronto-nasal process; Vth, trigeminal ganglion; VII-VIIIth, facial and auditory ganglia; ba, first branchial arch; lb, forelimb bud; drg, dorsal root ganglia.

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

6025_wholemount__moderate.wlz

6025_wholemount__notDetected.wlz

6025_wholemount__strong.wlz

6025_wholemount__possible.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:6025_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

cranial ganglion

detected

regional

Expression is detected in peripheral neurons of the craniofacial ganglia.

dorsal root ganglion

detected

regional

Expression is detected in the DRG flanking the spinal cord.

forelimb bud

detected

embryo

detected

regional

Expression is also detected in the developing craniofacial region.

fronto-nasal process

detected

trigeminal v ganglion

detected

facial vii ganglion

detected

acoustic viii ganglion

detected

Annotation Validation:

EMAGE Editor

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	Mycbp2 probeA
Entity Detected:	Mycbp2, MYC binding protein 2 ( MGI:2179432)
Sequence:	sense strand is shown >Mycbp2 probeA GGCATGGTCCTTAGCTAGAGACAGAGGCGGAAACCAGTACCTACGGCATGAAGATGAACAAGTTCTGCTG GATCAGAATTCTCAACCTCCTCCTCCAAGCCCTTTCTCAGTACAAGCTTTCAATAAAGGGGCAAGTTGCA GTGCCCAAGGATTTGACTATGGCCTGGGAAATAACAAAGGTGATCAACTGAGTGCCATATTGAATTCTAT TCAATCACGGCCCAATCTCCCAGCTCCTTCCATCTTTGATCAAGCTGCAAAACCTCCCTCTTCCCTAGTC CACAGCCCATTTGTGTTCGGACAGCCCCTTTCCTTCCAGCAGCGTCAGCTTCAGAGTGACAGAGGAACTA TCTCAACATCTTCAAGACCAGTGTCCACATCAGGGAAGTCAGAGCTGCCCTCTAAGCACAGCAGGTCAGT TAAACCCGACGGGCATGTGAGCCGGACTCCTGCTGACCAGAAGAAGCCACGGGGGACAGAAGGCTTATCT GCTAGTGAATCCCTCATGTTAAAATCTGATGCTGCAAAGTTGAGGTCAGACTCCCATAGTAGGTCCCTGT CCCCTAACCATAACACTCTGCAGACACTGAAGTCTGATGGGAGGACGTCTTCTGGCTTCAGGGCCGAATC CCCAGGACCAGGCTCGAGGTCATCCTCCCCTAAGCCCAAGCCTCTGCCGACTCCCAGGTCTAGCCCATCT GGTGCAAGCTCTCCACGCTCCTCCTCACCACAGGATAAAAATCTACCTCAGAAAAGCACAGCTCCTGCTA AGACAAAACTTGACCCACCTCGGGAACGTTCCAAGTCAGACTCATATACACTTGATCCAGATACCCTCCG TAAGAAGAAAATGCCCCTCACAGAACCATTAAGGGGGCGGTCCACATCACCAAAACCAAAACCAGTACCA AAGGATCCTAAAGACTCCCCAGGGTCTGAAAACAGAGCCCCTTCTCCCCACGTAGTGCAGGAAAACCTCC ACAGTGAGGTAGTTGAAGTCTGTACTTCAAGTACTTTAAAAACAAATGGTGTCACGGACAGCACCTGCGA TGACAGCGGTGACTTGAAGAGTGTGGATGAAGGTTCAAATAAAGTGCATTTCAGCATAGGCAAAGCACCG CTGAAAGATGAACAGGAAATGAGAGCATCACCCAAAATAAGTCGGAAGTGTGCTAACAGACACACCAGGC CCAAAAAAGAAAAGTCTAACTTCCTTTTCAAAGGAGATGGAACCAAATCTTTAGAACCAGCCAAGCAAGC CATGTCCCCGTCTGTGGCTGAGTGTGCCAGAGCCGTCTTTGCCTCTTTTTTGTGGCATGAAGGCATAGTA CATGATGCAATGGCTTGTTCTTCCTTCCTGAAATTTAATCCTGACCTTTCCAAAGAACATGCTCCTATAA GAAGTAGTTTGAATAGCCAACCACCCACAGAGGAAAAGGAAATCAAGTTAAAAAATAGACATTCATTGGA AATATCGTCTGCTCTGAATATGTTTAACATTGCACCTCATGGCCCAGATATA
	nt 8305 - nt 9826 of NM_207215.2
Notes:	The Mycbp2 (Phr1) probe used in this study by Burgess et al., 2004 [PMID:14729956] is described as relating to "nucleotides 8021 to 9542 of the coding sequence."
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Age:	10.5 dpc
Theiler Stage:	TS17
Mutations:	none (wild-type)
Preparation:	wholemount

Procedures

Fixation:	4% paraformaldehyde
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Burgess RW; Peterson KA; Johnson MJ; Roix JJ; Welsh IC; O'Brien TP, 2004 [PMID:14729956] , Indexed and Spatially Mapped by EMAGE.
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	non-screen
References:	[ doi:10.1128/MCB.24.3.1096-1105.2004] [ PMID:14729956] Burgess RW, Peterson KA, Johnson MJ, Roix JJ, Welsh IC, O'Brien TP 2004 Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. Mol Cell Biol (24):1096-105
Links:	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source