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EMAGE:6037

Prdm6 PR domain containing 6 ( MGI:2684938)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:6037
Figure 3G from [doi:10.1016/j.yjmcc.2007.06.008] J Mol Cell Cardiol 44(1):47-58. Wu Y; Ferguson JE rd; Wang H; Kelley R; Ren R; McDonough H; Meeker J; Charles PC; Wang H; Patterson C. PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. Copyright 2007. [PMID:17662997]

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:6037Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
6037_wholemount__moderate.wlz
6037_wholemount__weak.wlz
6037_wholemount__possible.wlz
6037_wholemount__notDetected.wlz
6037_wholemount__strong.wlz
(what is wlz format?)
Download all expression domains: EMAGE:6037_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
heart
detected detected
outflow tract
detected detected
Expression in the outflow track was evident at E9.5
extraembryonic vascular system
detected detected
regionalExpression in the yolk sac vasculature was evident at E9.5.
mesenchyme derived from splanchnopleure
detected detected
E9.5 showed characteristic staining in the para-aortic splanchnopleura (P-Sp)/aorto-gonadal-mesonephric (AGM) region.
genitourinary system
detected detected
E9.5 showed characteristic staining in the para-aortic splanchnopleura (P-Sp)/aorto-gonadal-mesonephric (AGM) region.
extraembryonic component
detected detected
E9.5 shows persistent staining of the allantois.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:Prdm6 probeA
Entity Detected:Prdm6, PR domain containing 6 ( MGI:2684938)
Notes:The Prdm6 probe used in this study by Wu et al., 2008 [PMID:17662997] is described as "a digoxigenin-labeled antisense RNA probe (from 165 bp to 1132 bp)." Editors note: The gene sequence that these base pair numbers refer to is not indicated by the authors.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:CD-1
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT
General Information
Authors:Wu Y; Ferguson JE rd; Wang H; Kelley R; Ren R; McDonough H; Meeker J; Charles PC; Wang H; Patterson C, 2008 [PMID:17662997] , Indexed and Spatially Mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1016/j.yjmcc.2007.06.008] [ PMID:17662997] Wu Y, Ferguson JE, Wang H, Kelley R, Ren R, McDonough H, Meeker J, Charles PC, Wang H, Patterson C 2008 PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. J Mol Cell Cardiol (44):47-58
Links: Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceEMAGE