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EMAGE:62

Pax2 paired box gene 2 ( MGI:97486)
TS15 (9.7 dpc)
in situ hybridisation

Data Images
EMAGE:62
Figure 4D of Martinez-Barbera et al., 2001 [PMID:11731459] . Copyright: This image is from Development and is displayed with the permission of the Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:62Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
62_wholemount_strong_3D_1.wlz
62_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:62_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
future brain
detected detected
regional
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1098114
Entity Detected:Pax2, paired box gene 2 ( MGI:97486)
Notes:Probe used in this study by Martinez-Barbera et al., 2001 [PMID:11731459] is referenced as being described by Acampora et al., 1997 [PMID:9342056] who in turn refer to Avantaggiato et al., 1996 [PMID:8626038] who describe the probe as corresponding to an "RT-PCR amplified product spanning the region between amino acids 325 and 518". Pax2 protein (GenBank ID P32114) is 415 aa.
Chemistry:RNA
Strand:antisense
Label:undefined
Specimen
Organism:mouse
Age:9.7 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Staining procedure:undefined
General Information
Authors:Martinez-Barbera et al., 2001 [PMID:11731459] Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:9342056] Acampora D, Avantaggiato V, Tuorto F, Simeone A 1997 Genetic control of brain morphogenesis through Otx gene dosage requirement. Development (124):3639-50
 [ PMID:11731459] Martinez-Barbera JP, Signore M, Boyl PP, Puelles E, Acampora D, Gogoi R, Schubert F, Lumsden A, Simeone A 2001 Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development (128):4789-800
 [ doi:10.1006/dbio.1996.0120] [ PMID:8626038] Avantaggiato V, Acampora D, Tuorto F, Simeone A 1996 Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Dev Biol (175):347-57
Links:MGI:2155566 same embryo
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI